Detalhe da pesquisa
1.
Impact of pemafibrate on lipid profile and insulin resistance in hypertriglyceridemic patients with coronary artery disease and metabolic syndrome.
Heart Vessels
; 39(6): 486-495, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38393377
2.
Effects of switching from sacubitril/valsartan to valsartan alone on plasma levels of natriuretic peptides and myocardial remodeling in heart failure with reduced ejection fraction.
BMC Cardiovasc Disord
; 23(1): 39, 2023 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36681789
3.
Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives.
Bioorg Med Chem
; 41: 116208, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34010766
4.
Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.
Bioorg Med Chem
; 34: 116034, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548803
5.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Proc Natl Acad Sci U S A
; 115(29): E6863-E6870, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967165
6.
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angew Chem Int Ed Engl
; 60(17): 9279-9283, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433953
7.
Impact of decreased insulin resistance by ezetimibe on postprandial lipid profiles and endothelial functions in obese, non-diabetic-metabolic syndrome patients with coronary artery disease.
Heart Vessels
; 34(6): 916-925, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30519809
8.
Characterisation of human induced pluripotent stem cell-derived endothelial cells under shear stress using an easy-to-use microfluidic cell culture system.
Biomed Microdevices
; 19(4): 91, 2017 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28994005
9.
Prognostic Impact of New-Onset Atrial Fibrillation in Patients With Chronic Heart Failure - A Report From the CHART-2 Study.
Circ J
; 80(1): 157-67, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26639067
10.
Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors.
Bioorg Med Chem
; 24(23): 6149-6165, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27825552
11.
Comprehensive Risk Stratification of Japanese Patients With Aortic Stenosis--A Proposal of a New Risk Score From the CHART-2 Study.
Circ J
; 79(7): 1631-8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25947000
12.
Improved Long-Term Prognosis of Dilated Cardiomyopathy With Implementation of Evidenced-Based Medication - Report From the CHART Studies - .
Circ J
; 79(6): 1332-41, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25833177
13.
Predictors and prognostic impact of post-traumatic stress disorder after the great East Japan earthquake in patients with cardiovascular disease.
Circ J
; 79(3): 664-7, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746552
14.
Temporal trends in clinical characteristics, management and prognosis of patients with symptomatic heart failure in Japan -- report from the CHART Studies.
Circ J
; 79(11): 2396-407, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26356834
15.
Prognostic Impact of Anemia in Patients With Chronic Heart Failure- With Special Reference to Clinical Background: Report From the CHART-2 Study.
Circ J
; 79(9): 1984-93, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26050711
16.
Prognostic Impact of Diabetes Mellitus in Chronic Heart Failure According to Presence of Ischemic Heart Disease With Special Reference to Nephropathy.
Circ J
; 79(8): 1764-72, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004750
17.
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities.
Bioorg Med Chem
; 23(15): 4544-4560, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100443
18.
Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1â³ binding site.
Bioorg Med Chem
; 22(19): 5487-505, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25192810
19.
Discovery of a novel series of indoline carbamate and indolinylpyrimidine derivatives as potent GPR119 agonists.
Bioorg Med Chem
; 22(5): 1649-66, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24508142
20.
Infectious Pulmonary Artery Pseudoaneurysm Secondary to a Lung Abscess Treated With Pulmonary Artery Coil Embolization: A Case Report.
Cureus
; 16(3): e55762, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38586669