Detalhe da pesquisa
1.
Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine.
Cell
; 158(3): 647-58, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25083874
2.
Nucleotide binding and conformational switching in the hexameric ring of a AAA+ machine.
Cell
; 153(3): 628-39, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622246
3.
AAA+ proteases: ATP-fueled machines of protein destruction.
Annu Rev Biochem
; 80: 587-612, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21469952
4.
Covalent linkage of distinct substrate degrons controls assembly and disassembly of DegP proteolytic cages.
Cell
; 145(1): 67-78, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458668
5.
Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine.
Cell
; 145(2): 257-67, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21496645
6.
The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery.
Proc Natl Acad Sci U S A
; 120(6): e2219044120, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36730206
7.
The membrane-cytoplasmic linker defines activity of FtsH proteases in Pseudomonas aeruginosa clone C.
J Biol Chem
; 300(2): 105622, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38176647
8.
Structure and function of ClpXP, a AAA+ proteolytic machine powered by probabilistic ATP hydrolysis.
Crit Rev Biochem Mol Biol
; 57(2): 188-204, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923891
9.
FtsH degrades kinetically stable dimers of cyclopropane fatty acid synthase via an internal degron.
Mol Microbiol
; 119(1): 101-111, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36456794
10.
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.
Cell
; 139(4): 744-56, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19914167
11.
Modular and coordinated activity of AAA+ active sites in the double-ring ClpA unfoldase of the ClpAP protease.
Proc Natl Acad Sci U S A
; 117(41): 25455-25463, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020301
12.
Multistep substrate binding and engagement by the AAA+ ClpXP protease.
Proc Natl Acad Sci U S A
; 117(45): 28005-28013, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106413
13.
Division of labor between the pore-1 loops of the D1 and D2 AAA+ rings coordinates substrate selectivity of the ClpAP protease.
J Biol Chem
; 297(6): 101407, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780718
14.
ClpP1P2 peptidase activity promotes biofilm formation in Pseudomonas aeruginosa.
Mol Microbiol
; 115(6): 1094-1109, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33231899
15.
A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites.
PLoS Biol
; 17(2): e3000136, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726238
16.
Mechanical Protein Unfolding and Degradation.
Annu Rev Physiol
; 80: 413-429, 2018 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29433415
17.
Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress.
Genes Dev
; 28(8): 902-11, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24736846
18.
Effect of directional pulling on mechanical protein degradation by ATP-dependent proteolytic machines.
Proc Natl Acad Sci U S A
; 114(31): E6306-E6313, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28724722
19.
The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol Cell
; 43(2): 217-28, 2011 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21777811
20.
Hinge-Linker Elements in the AAA+ Protein Unfoldase ClpX Mediate Intersubunit Communication, Assembly, and Mechanical Activity.
Biochemistry
; 57(49): 6787-6796, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30418765