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1.
Phys Rev Lett ; 131(15): 159901, 2023 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-37897792

RESUMO

This corrects the article DOI: 10.1103/PhysRevLett.128.164501.

2.
Phys Rev Lett ; 128(16): 164501, 2022 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-35522515

RESUMO

The large-scale flow structure and the turbulent transfer of heat and momentum are directly measured in highly turbulent liquid metal convection experiments for Rayleigh numbers varied between 4×10^{5} and ≤5×10^{9} and Prandtl numbers of 0.025≤Pr≤0.033. Our measurements are performed in two cylindrical samples of aspect ratios Γ=diameter/height=0.5 and 1 filled with the eutectic alloy GaInSn. The reconstruction of the three-dimensional flow pattern by 17 ultrasound Doppler velocimetry sensors detecting the velocity profiles along their beam lines in different planes reveals a clear breakdown of coherence of the large-scale circulation for Γ=0.5. As a consequence, the scaling laws for heat and momentum transfer inherit a dependence on the aspect ratio. We show that this breakdown of coherence is accompanied with a reduction of the Reynolds number Re. The scaling exponent ß of the power law Nu∝Ra^{ß} crosses eventually over from ß=0.221 to 0.124 when the liquid metal flow at Γ=0.5 reaches Ra≳2×10^{8} and the coherent large-scale flow is completely collapsed.

3.
Opt Lett ; 43(12): 2877-2880, 2018 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-29905713

RESUMO

We present a three-color femtosecond Er/Yb:fiber laser enabling highly specific and standardized nonlinear optical manipulation of live cells. The system simultaneously provides bandwidth-limited 80-fs pulses with identical intensity envelope centered at wavelengths of 515, 775, and 1035 nm in the focus of a confocal microscope. We achieve this goal by combining high-order dispersion control via, for example, chirped fiber Bragg gratings with proper bandwidth management in each nonlinear conversion step. Wavelength-selective and noninterfering induction of deoxyribonucleic acid (DNA) photoproducts and DNA strand breaks, as well as fluorescence photoactivation of a photoactivatable green fluorescent protein (PA-GFP)-histone fusion protein, are demonstrated. The capability to introduce different types of DNA lesions and perform photoswitching experiments in a selective manner is essential for quantitative studies on DNA repair and chromatin dynamics.


Assuntos
Cromatina/química , DNA/química , Tecnologia de Fibra Óptica/métodos , Lasers de Estado Sólido , Quebras de DNA de Cadeia Dupla , Desenho de Equipamento , Células HeLa , Humanos
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