Detalhe da pesquisa
1.
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.
Cell
; 154(4): 801-13, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23953112
2.
TGF-ß family ligands exhibit distinct signalling dynamics that are driven by receptor localisation.
J Cell Sci
; 132(14)2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217285
3.
Reply to "CRISPR screens are feasible in TP53 wild-type cells".
Mol Syst Biol
; 15(8): e9059, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31464368
4.
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility.
Nat Rev Mol Cell Biol
; 8(12): 970-82, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18000526
5.
CRISPR/Cas9 screening using unique molecular identifiers.
Mol Syst Biol
; 13(10): 945, 2017 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993443
6.
Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model.
EJNMMI Radiopharm Chem
; 9(1): 32, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637347
7.
Dynamical scenarios for chromosome bi-orientation.
Biophys J
; 104(12): 2595-606, 2013 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23790367
8.
An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.
Nat Commun
; 14(1): 5024, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596278
9.
Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.
J Biol Chem
; 286(9): 7648-60, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177872
10.
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action.
Front Oncol
; 12: 852980, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35530310
11.
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system.
Proc Natl Acad Sci U S A
; 105(18): 6608-13, 2008 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18443295
12.
Rapid genome editing by CRISPR-Cas9-POLD3 fusion.
Elife
; 102021 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34898428
13.
Designing custom CRISPR libraries for hypothesis-driven drug target discovery.
Comput Struct Biotechnol J
; 18: 2237-2246, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32952937
14.
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads.
Mol Cell Biol
; 25(22): 9845-58, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16260601
15.
CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response.
Nat Med
; 24(7): 927-930, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29892067
16.
Contribution of allelic imbalance to colorectal cancer.
Nat Commun
; 9(1): 3664, 2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30202008
17.
Structural insights into the DNA-binding specificity of E2F family transcription factors.
Nat Commun
; 6: 10050, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26632596
18.
Response to comment on "Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-ß pathway"-Smad2/3 activity does not predict the dynamics of transcription.
Sci Signal
; 7(344): lc2, 2014 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25249656
19.
Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-ß pathway.
Sci Signal
; 6(305): ra106, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24327760
20.
Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches.
Open Biol
; 1(3): 110009, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22645649