Detalhe da pesquisa
1.
Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins.
Cell
; 182(2): 345-356.e16, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589945
2.
Proteome-scale discovery of protein degradation and stabilization effectors.
Nature
; 628(8009): 878-886, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509365
3.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Mol Syst Biol
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580884
4.
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.
Cell
; 140(1): 148-60, 2010 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20074523
5.
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
Cell
; 143(4): 628-38, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074052
6.
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins.
Proc Natl Acad Sci U S A
; 119(17): e2119644119, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439056
7.
Translation from unconventional 5' start sites drives tumour initiation.
Nature
; 541(7638): 494-499, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28077873
8.
AJUBA: A regulator of epidermal homeostasis and cancer.
Exp Dermatol
; 30(4): 546-559, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33372298
9.
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
Nat Methods
; 14(12): 1191-1197, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29039415
10.
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.
Development
; 140(7): 1397-401, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23462470
11.
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.
Nature
; 468(7320): 98-102, 2010 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20881962
12.
A mouse model to identify cooperating signaling pathways in cancer.
Nat Methods
; 9(9): 897-900, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863881
13.
The NOTCH-RIPK4-IRF6-ELOVL4 Axis Suppresses Squamous Cell Carcinoma.
Cancers (Basel)
; 15(3)2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765696
14.
Mutational processes of tobacco smoking and APOBEC activity generate protein-truncating mutations in cancer genomes.
Sci Adv
; 9(44): eadh3083, 2023 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37922356
15.
Developmental priming of cancer susceptibility.
bioRxiv
; 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745326
16.
In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target.
Blood Cancer Discov
; 4(3): 180-207, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36763002
17.
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Cell Rep
; 42(10): 113256, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37847590
18.
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.
Nat Commun
; 14(1): 3150, 2023 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258521
19.
A designer peptide against the EAG2-Kvß2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma.
Nat Cancer
; 4(10): 1418-1436, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697045
20.
A CRISPR Path to Finding Vulnerabilities and Solving Drug Resistance: Targeting the Diverse Cancer Landscape and Its Ecosystem.
Adv Genet (Hoboken)
; 3(4): 2200014, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36911295