Detalhe da pesquisa
1.
Identification of sodium channel toxins from marine cone snails of the subgenera Textilia and Afonsoconus.
Cell Mol Life Sci
; 80(10): 287, 2023 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689602
2.
Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.
Proc Natl Acad Sci U S A
; 118(18)2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33893140
3.
Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant.
BMC Biol
; 21(1): 5, 2023 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36617555
4.
Structural and functional insights into the inhibition of human voltage-gated sodium channels by µ-conotoxin KIIIA disulfide isomers.
J Biol Chem
; 298(3): 101728, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167877
5.
Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific.
Bioconjug Chem
; 34(6): 1072-1083, 2023 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37262436
6.
Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.
J Biol Chem
; 295(15): 5067-5080, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139508
7.
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides.
Bioconjug Chem
; 32(11): 2407-2419, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34751572
8.
Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers.
Mol Pharm
; 18(3): 940-951, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33404254
9.
Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
J Am Chem Soc
; 142(50): 21178-21188, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33263997
10.
Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel NaV1.7 Inhibition.
Bioconjug Chem
; 31(1): 64-73, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790574
11.
Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors.
FASEB J
; 33(3): 3693-3703, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509130
12.
Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J Biol Chem
; 293(23): 9041-9052, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29703751
13.
Fluorescence Imaging of Peripheral Nerves by a Nav1.7-Targeted Inhibitor Cystine Knot Peptide.
Bioconjug Chem
; 30(11): 2879-2888, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647222
14.
Efficient Enzymatic Ligation of Inhibitor Cystine Knot Spider Venom Peptides: Using Sortase A To Form Double-Knottins That Probe Voltage-Gated Sodium Channel NaV1.7.
Bioconjug Chem
; 29(10): 3309-3319, 2018 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30148615
15.
Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods.
Mar Drugs
; 16(4)2018 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29621159
16.
Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
J Biol Chem
; 291(33): 17049-65, 2016 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27311819
17.
Development of a µO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J Biol Chem
; 291(22): 11829-42, 2016 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026701
18.
Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.
J Biol Chem
; 291(30): 15778-87, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226591
19.
Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating.
Biochim Biophys Acta
; 1858(4): 872-82, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26850736
20.
Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.
Biochim Biophys Acta Biomembr
; 1859(5): 835-844, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115115