Detalhe da pesquisa
1.
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Cell
; 184(13): 3502-3518.e33, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048700
2.
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91.
Mol Cell
; 84(5): 955-966.e4, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38325379
3.
GLP-1-directed NMDA receptor antagonism for obesity treatment.
Nature
; 629(8014): 1133-1141, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750368
4.
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis.
Nature
; 587(7832): 98-102, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116305
5.
Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors.
J Biol Chem
; 299(12): 105438, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37944618
6.
Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle.
Am J Physiol Endocrinol Metab
; 324(4): E289-E298, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36812387
7.
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4.
BMC Cancer
; 23(1): 1136, 2023 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993804
8.
Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction.
Allergy
; 77(9): 2677-2687, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122266
9.
Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1-induced satiation.
Diabetes Obes Metab
; 24(2): 268-280, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34658116
10.
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1.
Proc Natl Acad Sci U S A
; 116(14): 7123-7128, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30872479
11.
N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis.
Proc Natl Acad Sci U S A
; 116(49): 24770-24778, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740614
12.
Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms.
Am J Physiol Endocrinol Metab
; 320(5): E874-E885, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33645250
13.
Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase.
FASEB J
; 33(3): 3870-3886, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30508496
14.
Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity.
Am J Physiol Endocrinol Metab
; 316(3): E453-E463, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30562060
15.
Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice.
Am J Physiol Endocrinol Metab
; 317(6): E1081-E1093, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31503512
16.
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine.
Gastroenterology
; 155(4): 1164-1176.e2, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29935151
17.
EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.
Blood
; 129(7): 866-878, 2017 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003273
18.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.
Pharmacol Rev
; 67(2): 338-67, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25713288
19.
Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112.
FASEB J
; 30(5): 1836-48, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26823453
20.
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.
J Med Genet
; 53(9): 616-23, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068006