Detalhe da pesquisa
1.
Pragmatic mAb lead molecule engineering from a developability perspective.
Biotechnol Bioeng
; 118(10): 3733-3743, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33913507
2.
The challenge of applying Raman spectroscopy to monitor recombinant antibody production.
Analyst
; 138(22): 6977-85, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24093128
3.
Metabolite profiling of recombinant CHO cells: designing tailored feeding regimes that enhance recombinant antibody production.
Biotechnol Bioeng
; 108(12): 3025-31, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21769861
4.
Rapid characterization of N-linked glycans from secreted and gel-purified monoclonal antibodies using MALDI-ToF mass spectrometry.
Biotechnol Bioeng
; 107(5): 902-8, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20661906
5.
Rapid monitoring of recombinant antibody production by mammalian cell cultures using fourier transform infrared spectroscopy and chemometrics.
Biotechnol Bioeng
; 106(3): 432-42, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20198655
6.
Eukaryotic transcription factors as direct nutrient sensors.
Trends Biochem Sci
; 30(7): 405-12, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15950477
7.
At-line high throughput site-specific glycan profiling using targeted mass spectrometry.
Biotechnol Rep (Amst)
; 25: e00424, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071892
8.
Effective quenching processes for physiologically valid metabolite profiling of suspension cultured Mammalian cells.
Anal Chem
; 81(1): 174-83, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19061395
9.
Nutrient-regulated gene expression in eukaryotes.
Biochem Soc Symp
; (73): 85-96, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16626290
10.
Metabolomics reveals the physiological response of Pseudomonas putida KT2440 (UWC1) after pharmaceutical exposure.
Mol Biosyst
; 12(4): 1367-77, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26932201
11.
Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness.
Biotechnol J
; 10(9): 1434-45, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198903
12.
Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling.
Nat Protoc
; 6(8): 1241-9, 2011 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21799492
13.
The effect of ligand binding on the galactokinase activity of yeast Gal1p and its ability to activate transcription.
J Biol Chem
; 284(1): 229-236, 2009 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18957435
14.
Galactose metabolism in yeast-structure and regulation of the leloir pathway enzymes and the genes encoding them.
Int Rev Cell Mol Biol
; 269: 111-50, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18779058
15.
Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.
J Biol Chem
; 282(3): 1534-8, 2007 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17121853
16.
Contribution of amino acid side chains to sugar binding specificity in a galactokinase, Gal1p, and a transcriptional inducer, Gal3p.
J Biol Chem
; 281(25): 17150-17155, 2006 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16603548
17.
Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer.
J Biol Chem
; 280(44): 36905-11, 2005 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16115868
18.
Modulation of transcription factor function by an amino acid: activation of Put3p by proline.
EMBO J
; 22(19): 5147-53, 2003 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14517252