RESUMO
BACKGROUND: The objective was to describe the main causes of hospitalization in people with Angelman syndrome (AS). METHOD: Population-based cross-sectional study in the Community of Madrid (CM), Spain. The information source for AS cases was the information system for rare diseases in the CM. Variables related to hospitalization, for the period 2006-2014, were the following: number of episodes, outcome, main cause, length of stay and type of admission. Main causes of hospitalization were described by age group and sex. RESULTS: The most frequent causes of hospitalization were the following: oral-dental care (28.9%), seizures (19.6%), orthopaedic problems (14.4%) and acute respiratory disorders (12.4%). The percentage of hospitalizations was higher for oral-dental care in women and for orthopaedic problems in men (p-value <.05). Hospitalizations for an acute respiratory disorder were higher in adults (p-value <.05). CONCLUSIONS: Some differences in the causes of hospitalization of people with AS were observed by sex and age.
Assuntos
Síndrome de Angelman/complicações , Hospitalização , Doenças Musculoesqueléticas/complicações , Transtornos Respiratórios/complicações , Convulsões/complicações , Adolescente , Adulto , Fatores Etários , Idoso , Criança , Estudos Transversais , Assistência Odontológica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores Sexuais , Adulto JovemRESUMO
The appearance of the SARS CoV-2 virus and the associated COVID-19 pandemic has been associated with the onset of mental disorders in healthy people and the worsening in those with pre-existing mental conditions. One of the areas that has raised the greatest concern is that of suicidality. Most of the published studies have been carried out cross-sectional or with small samples, without stratifying by age and gender. Thus, the aim of this longitudinal research is to study, in a large population sample of around 6,700,000 inhabitants belonging to the entire region of Madrid (Spain), the admissions in psychiatric hospitalization units due to suicidal attempts along 2019, 2020 and 2021. No clear increase in the number of admissions due to suicidality in the total population have been found. In addition, a higher prevalence in admissions among women is verified. Moreover, stratifying by age and gender, a striking and significant increase in hospital admissions due to suicidality has been observed in the group up to 17 years old, from September 2020 until the end of the study. These results highlight the special vulnerability of children and adolescents, specifically girls, and the need for preventive measures in the face of future pandemics.
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COVID-19 , Tentativa de Suicídio , Adolescente , Criança , Humanos , Feminino , Tentativa de Suicídio/psicologia , Pandemias , Estudos Longitudinais , Estudos Transversais , Ideação Suicida , Hospitalização , HospitaisRESUMO
BACKGROUND AND OBJECTIVE: Lung cancer causes high morbimortality in Spain and is currently experiencing a significant increase in women. The aim of this study was to describe differential clinical and health care characteristics by sex, as well as factors associated with and geographic differences of in-hospital mortality. MATERIAL AND METHOD: Descriptive study of episodes registered in the National Hospital Discharge Minimum Basic Data Set for admission type and gender in 2005. Two logistic regression models by sex were built in order to explain the individual influence of variables on in-hospital mortality. Using predictive values of the models, standardized mortality rates were calculated to study the variation between Spanish regions. RESULTS: Women presented a lower mean age, smoking habit and in-hospital mortality than men. However, women presented more adenocarcinomas, greater care in high volume centers, more surgery in readmissions and were subjected to chemotherapy more often in new admissions than men. Adenocarcinoma in men and no specific location in women were associated with higher mortality. Smoking habit and lung diagnosis procedures in men, and middle lobe location and bronchoscopy in women were associated with lower mortality. The geographical mortality pattern detected was similar in both sexes only in some regions of Spain. CONCLUSIONS: Differential clinical characteristics, health care and overall results appear to exist depending on individuals' gender. Recognition of these differences are crucial in order to improve the effectiveness and equity of our health care system.
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Mortalidade Hospitalar , Neoplasias Pulmonares/mortalidade , Idoso , Feminino , Humanos , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/terapia , Masculino , Pessoa de Meia-Idade , EspanhaRESUMO
BACKGROUND: Intragastric balloons have been used since 1985 to treat obesity, but an evidence-based systematic review had not been previously performed. The objective of this study is to determine the safety, efficacy, and effectiveness of the most widely used balloon, BioEnterics Intragastric Balloon (BIB), to treat obesity. METHODS: Systematic literature review of Medline, Embase, and other information sources from inception to March 2006. The quality of selected studies was assessed. Meta-analysis of weighted mean difference was made using the inverse variance method. RESULTS: We pooled 15 articles (3,608 patients) to estimate BIBs effectiveness. The estimates for weight lost at balloon removal for BIB were the following: 14.7 kg, 12.2% of initial weight, 5.7 kg/m(2), and 32.1% of excess weight. However, data were scant after balloon removal. Yet, efficacy at balloon removal was estimated with a meta-analysis of two randomized controlled trials (75 patients) that compared balloon versus placebo, indicating the balloon group lost more weight than the placebo group. These differences in weight lost were 6.7 kg, 1.5% of initial weight, 3.2 kg/m(2), and 17.6% of excess weight. Regarding BIB safety, the majority of complications were mild and the early removal rate was 4.2%. CONCLUSION: The use of the BIB, within a multidisciplinary weight management program, is a short-term effective treatment to lose weight, but it is not yet possible to verify its capacity to maintain the weight lost over a long period of time.
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Balão Gástrico , Obesidade/terapia , Remoção de Dispositivo , Balão Gástrico/efeitos adversos , Humanos , Resultado do Tratamento , Redução de PesoRESUMO
BACKGROUND: Pancreatic cancer is becoming an increasingly important health problem in Spain. This study aimed to analyze the hospital management of this process and the factors associated with mortality by using an administrative data base. MATERIAL AND METHOD: We performed a descriptive study. Socio-demographic, clinical, diagnostic, and therapeutic variables of episodes registered in the national Hospital Discharge Minimum Data Set for 2004 were gathered. Comorbidity was assessed with the Charlson index. A logistic regression model was built to explain the individual influence of variables on in-hospital mortality. Mortality in the 17 autonomous regions of Spain was analyzed by using standardized mortality rates, through predicted mortality obtained from the multivariate model. RESULTS: The mean age was 68 years and men represented 56%. Readmissions accounted for 80% of the cases. The most frequent localization was in the pancreatic head and the most frequently employed procedures were computed tomography and surgery. In-hospital mortality was 25%, was higher in men, and increased with age. Mortality was higher in new admissions than in readmissions. Factors associated with higher mortality in the multivariate analysis were male sex, age, unspecified location or location in the tail, emergency admission, hospital stay, and comorbidity. Observed mortality was higher than expected in the Canary Islands and Madrid and was lower than expected in Catalonia and the Valencian Community. DISCUSSION: Future studies with more detailed information should be performed to allow the factors associated with in-hospital mortality from pancreatic cancer to be confirmed and to clarify the reasons for the geographical differences identified.
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Mortalidade Hospitalar , Neoplasias Pancreáticas/mortalidade , Adulto , Idoso , Feminino , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Pancreáticas/diagnóstico , Neoplasias Pancreáticas/terapia , EspanhaRESUMO
INTRODUCTION: Suicide is a major public health problem worldwide, and an approach is necessary due to its high potential for prevention. This paper examines the main characteristics of people admitted to hospitals in the Community of Madrid (Spain) with suicidal behaviour, and the factors associated with their hospital mortality. MATERIAL AND METHODS: A study was conducted on patients with E950-E959 codes of suicide and self-inflicted injuries of the International Classification of Diseases, Ninth Revision, Clinical Modification, contained in any diagnostic field of the minimum basic data set at hospital discharge between 2003 and 2013. Sociodemographic, clinical and health care variables were assessed by uni- and multivariate logistic regression analysis in the evaluation of factors associated with hospital mortality. RESULTS: Hospital suicidal behaviour predominates in women (58.7%) and in middle-age. Hospital mortality is 2.2% (1.6% in women and 3.2% in men), increasing with age. Mental disorders are detected 3-4 times more in secondary diagnoses. The main primary diagnosis (>74%) is poisoning with substances, with lower mortality (â¼1%) than injury by hanging and jumping from high places (≥12%), which have the highest numbers. Other factors associated with increased mortality include different medical comorbidities and severity of the injury, while length of stay and mental disorders are protective factors. Type of hospital, poisoning, and Charlson index are associated differently with mortality in men and women. CONCLUSIONS: Hospitalised suicidal acts show a low mortality, mainly related to comorbidities and the severity of injuries.
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Mortalidade Hospitalar , Tentativa de Suicídio/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Espanha/epidemiologia , Suicídio/estatística & dados numéricos , Tentativa de Suicídio/psicologia , Adulto JovemRESUMO
BACKGROUND: Acute myocardial infarction has a major bearing on morbimortality in developed countries. This study is aimed at developing a risk adjustment model for assessing the results of managing this disease and comparing how this management is carried out with other models. METHODS: A risk adjustment model is developed for acute myocardial infarction by means of logistic regression with the information from an administrative database including various Spanish hospitals, taking the intrahospital mortality rate as the response variable and variables inherent to the patient proper as predictive variables. The predictability thereof is compared to the Charlson Model and the ICES model. These models are applied for assessing the intrahospital mortality rate. RESULTS: The age (OR: 1.07), the anterolateral location (OR: 2.32) and inferoposterior location (OR: 1.91), cardiogenic shock (OR: 39.99), arrhythmia (OR: 94.43), cerebrovascular disease (OR: 2.15) and kidney failure (OR: 1.87) are shown to be related to a higher risk of death. The model developed provides a better predictability (-2LL: 2240) than the Charlson model (-2LL: 3073) and the ICES model (-2LL: 2366). There are no significant differences in the risk-adjusted death rate for the 23 hospitals studied, nor any differences between public and private hospitals nor the care volume or technological level. Coronariography (RMAR: 0.66) and percutaneous coronary interventions (RMAR: 0.69) are procedures having a protective effect. CONCLUSIONS: The model developed may be a useful tool for assessing the hospital care provided for myocardial infarction.
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Modelos Estatísticos , Infarto do Miocárdio/epidemiologia , Infarto do Miocárdio/terapia , Feminino , Humanos , Masculino , Medição de Risco , EspanhaRESUMO
INTRODUCTION: Immigration is a phenomenon with a significant impact on mental health. The aims of this study were to describe health care characteristics, time trends, differences among Immigrant, and diagnoses associated with new outpatient psychiatric consultation Immigrant in Segovia. METHODS: A descriptive study of new consultations with sociodemographic, health care and clinical variables computerized records from the «Antonio Machado¼ Mental Health Center for 2001-2002 and 2008 comparing immigrant and Spanish population. Population incidences were calculated by sex, geographic regions and countries of origin. By multivariate logistic regression assessed the relationship between ICD-10 diagnoses and immigration. RESULTS: Immigrants had an average age 10 years younger than the Spanish. Incidence rate of new consultation was always higher in women, decreased in immigrants and increased in the Spanish between 2001 and 2008. South Central Americans and Eastern Europeans had the highest and lowest rates of new visits, respectively. Bulgaria, Morocco, Romania and Poland were the countries most representative in 2008, with low incidences. Neurotic and somatoform disorders were the most common regardless of the origin of the patient. Psychotic and personality disorders were positively associated with immigration in the multivariate analysis. CONCLUSIONS: The attention of mental health immigrants in Segovia is characterized by young age, lower incidence of new queries with important variations between regions, and diagnostic association with processes more severe, which may reflect underdiagnosis and underutilization phenomena.