Detalhe da pesquisa
1.
The origin of human mutation in light of genomic data.
Nat Rev Genet
; 22(10): 672-686, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34163020
2.
Author Correction: The origin of human mutation in light of genomic data.
Nat Rev Genet
; 22(10): 687, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34376821
3.
Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.
Genome Res
; 27(8): 1336-1343, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512192
4.
APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.
Genome Res
; 27(2): 175-184, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27940951
5.
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.
Genome Res
; 26(2): 174-82, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755635
6.
Evolution of Local Mutation Rate and Its Determinants.
Mol Biol Evol
; 34(5): 1100-1109, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28138076
7.
Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours.
J Pathol
; 243(3): 331-341, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28805995
8.
Gene age predicts the strength of purifying selection acting on gene expression variation in humans.
Am J Hum Genet
; 95(6): 660-74, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480033
9.
Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.
Mol Biol Evol
; 32(12): 3158-72, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26376651
10.
Extraordinary Genetic Diversity in a Wood Decay Mushroom.
Mol Biol Evol
; 32(10): 2775-83, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26163667
11.
Crossing-over in a hypervariable species preferentially occurs in regions of high local similarity.
Mol Biol Evol
; 31(11): 3016-25, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25135947
12.
Prevalence of multinucleotide replacements in evolution of primates and Drosophila.
Mol Biol Evol
; 30(6): 1315-25, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447710
13.
Discovery of recessive effect of human polymerase δ proofreading deficiency through mutational analysis of POLD1-mutated normal and cancer cells.
Eur J Hum Genet
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38658779
14.
Heterogeneity of the transition/transversion ratio in Drosophila and Hominidae genomes.
Mol Biol Evol
; 29(8): 1943-55, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22337862
15.
A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription.
Nat Genet
; 55(12): 2235-2242, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036792
16.
Population sequencing data reveal a compendium of mutational processes in the human germ line.
Science
; 373(6558): 1030-1035, 2021 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385354
17.
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations.
Nat Genet
; 51(1): 36-41, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30510240
18.
Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence.
Nat Genet
; 50(4): 487-492, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507425
19.
Publisher Correction: Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence.
Nat Genet
; 53(8): 1270, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34302146
20.
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma.
Nat Genet
; 48(4): 398-406, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26950094