Detalhe da pesquisa
1.
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation.
Proc Natl Acad Sci U S A
; 121(1): e2307086120, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38147543
2.
HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide.
Nat Immunol
; 12(1): 54-61, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21131964
3.
Modeling the clinical phenotype of BTK inhibition in the mature murine immune system.
J Immunol
; 193(1): 185-97, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899507
4.
Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis.
J Immunol
; 191(9): 4540-50, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068666
5.
Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem J
; 460(2): 211-22, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24593284
6.
Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I.
Biotechnol Bioeng
; 109(7): 1723-34, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22252477
7.
Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys.
Rheumatology (Oxford)
; 50(6): 1033-44, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21258049
8.
Suppression of autoimmune diabetes by soluble galectin-1.
J Immunol
; 182(5): 2641-53, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19234158
9.
In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.
J Immunol
; 182(10): 6342-52, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19414787
10.
Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection.
J Virol
; 82(10): 5109-14, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18337576
11.
Prevention of type 1 diabetes by gene therapy.
J Clin Invest
; 114(7): 969-78, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15467836
12.
Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers.
J Clin Invest
; 112(6): 831-42, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12975468
13.
Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia.
Cancer Res
; 65(21): 10050-8, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16267031
14.
Self-reactive human CD4 T cell clones form unusual immunological synapses.
J Exp Med
; 209(2): 335-52, 2012 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22312112
15.
Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with nanomolar potency in a whole-blood assay.
J Med Chem
; 55(22): 10047-63, 2012 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23098091
16.
Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence.
J Clin Invest
; 120(4): 1324-36, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20200448
17.
Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide.
J Infect Dis
; 196(12): 1761-72, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18190256
18.
Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1.
EMBO J
; 26(4): 1187-97, 2007 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17268555
19.
Small molecules that enhance the catalytic efficiency of HLA-DM.
J Immunol
; 176(7): 4208-20, 2006 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16547258
20.
Expansion and contraction of HIV-specific CD4 T cells with short bursts of viremia, but physical loss of the majority of these cells with sustained viral replication.
J Immunol
; 175(10): 6948-58, 2005 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16272355