Detalhe da pesquisa
1.
Fab-Nanolipoprotein Conjugate Causes Vitreous Opacity and Cataracts Following a Single Intravitreal Administration in New Zealand White Rabbits.
Toxicol Pathol
; 49(3): 647-655, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733956
2.
Nanolipoprotein Particles as a Delivery Platform for Fab Based Therapeutics.
Bioconjug Chem
; 31(8): 1995-2007, 2020 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32701261
3.
In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.
Mol Pharm
; 16(1): 86-95, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444371
4.
Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.
Mol Pharm
; 13(9): 2996-3003, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27244474
5.
Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.
J Biol Chem
; 288(37): 26583-93, 2013 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23880771
6.
Nanolipoprotein particles for co-delivery of cystine-knot peptides and Fab-based therapeutics.
Nanoscale Adv
; 3(13): 3929-3941, 2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36133017
7.
Data on charge separation of bispecific and mispaired IgGs using native charge-variant mass spectrometry.
Data Brief
; 30: 105435, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32274410
8.
Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases.
Expert Opin Drug Deliv
; 16(1): 43-57, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30488721
9.
Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules.
Transl Vis Sci Technol
; 8(6): 1, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31695962
10.
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
PLoS One
; 14(6): e0218613, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31251757
11.
Impact of polymer geometry on the interactions of protein-PEG conjugates.
Biophys Chem
; 236: 22-30, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29331201
12.
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
MAbs
; 9(8): 1297-1305, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28854082
13.
An efficient route to bispecific antibody production using single-reactor mammalian co-culture.
MAbs
; 8(8): 1487-1497, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27680183
14.
Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.
Invest Ophthalmol Vis Sci
; 56(9): 5390-400, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26275136
15.
Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity.
MAbs
; 5(6): 872-81, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23995614
16.
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies.
Nat Biotechnol
; 31(8): 753-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23831709
17.
Long-range structural and dynamical changes induced by cofactor binding in DNA methyltransferase M.HhaI.
Biochemistry
; 46(24): 7261-8, 2007 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17523600