Pesquisa | BVS IEC

1.

Stress-Induced Metabolic Disorder in Peripheral CD4⁺ T Cells Leads to Anxiety-like Behavior.

Fan, Ke-Qi; Li, Yi-Yuan; Wang, Hao-Li; Mao, Xin-Tao; Guo, Jin-Xin; Wang, Fei; Huang, Ling-Jie; Li, Yi-Ning; Ma, Xiang-Yu; Gao, Zheng-Jun; Chen, Wei; Qian, Dan-Dan; Xue, Wen-Jin; Cao, Qian; Zhang, Lei; Shen, Li; Zhang, Long; Tong, Chao; Zhong, Jiang-Yan; Lu, Wei; Lu, Ling; Ren, Ke-Ming; Zhong, Guisheng; Wang, Yuan; Tang, Mingliang; Feng, Xin-Hua; Chai, Ren-Jie; Jin, Jin.

Cell ; 179(4): 864-879.e19, 2019 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-31675497

2.

Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression.

Sattiraju, Anirudh; Kang, Sangjo; Giotti, Bruno; Chen, Zhihong; Marallano, Valerie J; Brusco, Concetta; Ramakrishnan, Aarthi; Shen, Li; Tsankov, Alexander M; Hambardzumyan, Dolores; Friedel, Roland H; Zou, Hongyan.

Immunity ; 56(8): 1825-1843.e6, 2023 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-37451265

3.

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.

Wang, Guangchuan; Chow, Ryan D; Bai, Zhigang; Zhu, Lvyun; Errami, Youssef; Dai, Xiaoyun; Dong, Matthew B; Ye, Lupeng; Zhang, Xiaoya; Renauer, Paul A; Park, Jonathan J; Shen, Li; Ye, Hanghui; Fuchs, Charles S; Chen, Sidi.

Nat Immunol ; 20(11): 1494-1505, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31611701

4.

Circulating myeloid-derived MMP8 in stress susceptibility and depression.

Cathomas, Flurin; Lin, Hsiao-Yun; Chan, Kenny L; Li, Long; Parise, Lyonna F; Alvarez, Johana; Durand-de Cuttoli, Romain; Aubry, Antonio V; Muhareb, Samer; Desland, Fiona; Shimo, Yusuke; Ramakrishnan, Aarthi; Estill, Molly; Ferrer-Pérez, Carmen; Parise, Eric M; Wilk, C Matthias; Kaster, Manuella P; Wang, Jun; Sowa, Allison; Janssen, William G; Costi, Sara; Rahman, Adeeb; Fernandez, Nicolas; Campbell, Matthew; Swirski, Filip K; Nestler, Eric J; Shen, Li; Merad, Miriam; Murrough, James W; Russo, Scott J.

Nature ; 626(8001): 1108-1115, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38326622

5.

Mechanism and function of oxidative reversal of DNA and RNA methylation.

Shen, Li; Song, Chun-Xiao; He, Chuan; Zhang, Yi.

Annu Rev Biochem ; 83: 585-614, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24905787

6.

Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2.

Li, Yuhuan; Kang, Sangjo; Halawani, Dalia; Wang, Yiqun; Junqueira Alves, Chrystian; Ramakrishnan, Aarthi; Estill, Molly; Shen, Li; Li, Fengtao; He, Xijing; Friedel, Roland H; Zou, Hongyan.

Genes Dev ; 36(3-4): 133-148, 2022 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-35086862

7.

Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.

Matoba, Shogo; Liu, Yuting; Lu, Falong; Iwabuchi, Kumiko A; Shen, Li; Inoue, Azusa; Zhang, Yi.

Cell ; 159(4): 884-95, 2014 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-25417163

8.

Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.

Shen, Li; Wu, Hao; Diep, Dinh; Yamaguchi, Shinpei; D'Alessio, Ana C; Fung, Ho-Lim; Zhang, Kun; Zhang, Yi.

Cell ; 153(3): 692-706, 2013 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-23602152

9.

HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity.

Yuan, Bo; Liu, Jinquan; Shi, Aiping; Cao, Jin; Yu, Yi; Zhu, Yezhang; Zhang, Chengbin; Qiu, Yifei; Luo, Hongjie; Shi, Jiaxian; Cao, Xiaolei; Xu, Pinglong; Shen, Li; Liang, Tingbo; Zhao, Bin; Feng, Xin-Hua.

EMBO J ; 42(4): e111549, 2023 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-36598329

10.

Single-cell transcriptomics of LepR-positive skeletal cells reveals heterogeneous stress-dependent stem and progenitor pools.

Mo, Chunyang; Guo, Jingxin; Qin, Jiachen; Zhang, Xiaoying; Sun, Yuxi; Wei, Hanjing; Cao, Dandan; Zhang, Yiying; Zhao, Chengchen; Xiong, Yanhong; Zhang, Yong; Sun, Yao; Shen, Li; Yue, Rui.

EMBO J ; 41(4): e108415, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-34957577

11.

Genomic loci influence patterns of structural covariance in the human brain.

Wen, Junhao; Nasrallah, Ilya M; Abdulkadir, Ahmed; Satterthwaite, Theodore D; Yang, Zhijian; Erus, Guray; Robert-Fitzgerald, Timothy; Singh, Ashish; Sotiras, Aristeidis; Boquet-Pujadas, Aleix; Mamourian, Elizabeth; Doshi, Jimit; Cui, Yuhan; Srinivasan, Dhivya; Skampardoni, Ioanna; Chen, Jiong; Hwang, Gyujoon; Bergman, Mark; Bao, Jingxuan; Veturi, Yogasudha; Zhou, Zhen; Yang, Shu; Dazzan, Paola; Kahn, Rene S; Schnack, Hugo G; Zanetti, Marcus V; Meisenzahl, Eva; Busatto, Geraldo F; Crespo-Facorro, Benedicto; Pantelis, Christos; Wood, Stephen J; Zhuo, Chuanjun; Shinohara, Russell T; Gur, Ruben C; Gur, Raquel E; Koutsouleris, Nikolaos; Wolf, Daniel H; Saykin, Andrew J; Ritchie, Marylyn D; Shen, Li; Thompson, Paul M; Colliot, Olivier; Wittfeld, Katharina; Grabe, Hans J; Tosun, Duygu; Bilgel, Murat; An, Yang; Marcus, Daniel S; LaMontagne, Pamela; Heckbert, Susan R.

Proc Natl Acad Sci U S A ; 120(52): e2300842120, 2023 Dec 26.

Artigo em Inglês | MEDLINE | ID: mdl-38127979

12.

Circuit-wide gene network analysis reveals sex-specific roles for phosphodiesterase 1b in cocaine addiction.

Teague, Collin D; Markovic, Tamara; Zhou, Xianxiao; Martinez-Rivera, Freddyson J; Minier-Toribio, Angelica; Zinsmaier, Alexander; Pulido, Nathalia V; Schmidt, Kyra H; Lucerne, Kelsey E; Godino, Arthur; van der Zee, Yentl Y; Ramakrishnan, Aarthi; Futamura, Rita; Browne, Caleb J; Holt, Leanne M; Yim, Yun Young; Azizian, Corrine H; Walker, Deena M; Shen, Li; Dong, Yan; Zhang, Bin; Nestler, Eric J.

J Neurosci ; 2024 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-38637154

13.

Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons.

De Gregorio, Roberto; Subah, Galadu; Chan, Jennifer C; Speranza, Luisa; Zhang, Xiaolei; Ramakrishnan, Aarthi; Shen, Li; Maze, Ian; Stanton, Patric K; Sze, Ji Y.

Development ; 149(21)2022 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-36178075

14.

Integrative analysis of multi-omics and imaging data with incorporation of biological information via structural Bayesian factor analysis.

Bao, Jingxuan; Chang, Changgee; Zhang, Qiyiwen; Saykin, Andrew J; Shen, Li; Long, Qi.

Brief Bioinform ; 24(2)2023 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-36882008

15.

Suppression of AGRN enhances CD8+ T cell recruitment and inhibits breast cancer progression.

Tao, Jing; Shen, Li; Zhuang, Minyu; Zhai, Changyuan; Zeng, Hanling; Mao, Yuan; Liu, Xiaoan.

FASEB J ; 38(7): e23582, 2024 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-38568853

16.

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.

Farrelly, Lorna A; Thompson, Robert E; Zhao, Shuai; Lepack, Ashley E; Lyu, Yang; Bhanu, Natarajan V; Zhang, Baichao; Loh, Yong-Hwee E; Ramakrishnan, Aarthi; Vadodaria, Krishna C; Heard, Kelly J; Erikson, Galina; Nakadai, Tomoyoshi; Bastle, Ryan M; Lukasak, Bradley J; Zebroski, Henry; Alenina, Natalia; Bader, Michael; Berton, Olivier; Roeder, Robert G; Molina, Henrik; Gage, Fred H; Shen, Li; Garcia, Benjamin A; Li, Haitao; Muir, Tom W; Maze, Ian.

Nature ; 567(7749): 535-539, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30867594

17.

The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting.

Lee, Chen-Cheng; Peng, Shih-Huan; Shen, Li; Lee, Chung-Fan; Du, Ting-Huei; Kang, Ming-Lun; Xu, Guo-Liang; Upadhyay, Anup K; Cheng, Xiaodong; Yan, Yu-Ting; Zhang, Yi; Juan, Li-Jung.

Mol Cell ; 68(1): 89-103.e7, 2017 Oct 05.

Artigo em Inglês | MEDLINE | ID: mdl-28943313

18.

TGM2-mediated histone transglutamination is dictated by steric accessibility.

Lukasak, Bradley J; Mitchener, Michelle M; Kong, Lingchun; Dul, Barbara E; Lazarus, Cole D; Ramakrishnan, Aarthi; Ni, Jizhi; Shen, Li; Maze, Ian; Muir, Tom W.

Proc Natl Acad Sci U S A ; 119(43): e2208672119, 2022 10 25.

Artigo em Inglês | MEDLINE | ID: mdl-36256821

19.

RGS4 Actions in Mouse Prefrontal Cortex Modulate Behavioral and Transcriptomic Responses to Chronic Stress and Ketamine.

Mitsi, Vasiliki; Ruiz, Anne; Polizu, Claire; Farzinpour, Zahra; Ramakrishnan, Aarthi; Serafini, Randal A; Parise, Eric M; Floodstrand, Madeline; Sial, Omar K; Gaspari, Sevasti; Tang, Cheuk Y; Nestler, Eric J; Schmidt, Eric F; Shen, Li; Zachariou, Venetia.

Mol Pharmacol ; 105(4): 272-285, 2024 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-38351270

20.

Chromatin accessibility and H3K9me3 landscapes reveal long-term epigenetic effects of fetal-neonatal iron deficiency in rat hippocampus.

Liu, Shirelle X; Ramakrishnan, Aarthi; Shen, Li; Gewirtz, Jonathan C; Georgieff, Michael K; Tran, Phu V.

BMC Genomics ; 25(1): 301, 2024 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-38515015

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Instituto Evandro Chagas

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