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The geographic distribution of plant diversity matches the gradient of habitat heterogeneity from lowlands to mountain regions. However, little is known about how much this relationship is conserved across scales. Using the World Checklist of Vascular Plants and high-resolution biodiversity maps developed by species distribution models, we investigated the associations between species richness and habitat heterogeneity at the scales of Eurasia and the Hengduan Mountains (HDM) in China. Habitat heterogeneity explains seed plant species richness across Eurasia, but the plant species richness of 41/97 HDM families is even higher than expected from fitted statistical relationships. A habitat heterogeneity index combining growing degree days, site water balance, and bedrock type performs better than heterogeneity based on single variables in explaining species richness. In the HDM, the association between heterogeneity and species richness is stronger at larger scales. Our findings suggest that high environmental heterogeneity provides suitable conditions for the diversification of lineages in the HDM. Nevertheless, habitat heterogeneity alone cannot fully explain the distribution of species richness in the HDM, especially in the western HDM, and complementary mechanisms, such as the complex geological history of the region, may have contributed to shaping this exceptional biodiversity hotspot.
Assuntos
Ecossistema , Traqueófitas , Humanos , Biodiversidade , Plantas , SementesRESUMO
Probability density forecast offers the whole distributions of forecasting targets, which brings greater flexibility and practicability than the other probabilistic forecast models such as prediction interval (PI) and quantile forecast. However, existing density forecast models have introduced various constraints on forecasted distributions, which has limited their ability to approximate real distributions and may result in suboptimality. In this paper, a distribution-free density forecast model based on deep learning is proposed, in which the real cumulative density functions (CDFs) of forecasting target are approximated by a large-capacity positive-weighted deep neural network (NN). Benefiting from the universal approximation ability of NNs, the range of forecasted distributions has been proven to contain all the distributions with continuous CDFs, which is superior to existing models' considering both width and accordance with reality. Three tests from different scenarios were implemented for evaluation, i.e., very-short-term wind power, wind speed, and day-ahead electricity price forecast, in which the proposed density forecast model has shown superior performance over the state of the art.
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Heterogeneity broadly exists in various cell types both during development and at homeostasis. Investigating heterogeneity is crucial for comprehensively understanding the complexity of ontogeny, dynamics, and function of specific cell types. Traditional bulk-labeling techniques are incompetent to dissect heterogeneity within cell population, while the new single-cell lineage tracing methodologies invented in the last decade can hardly achieve high-fidelity single-cell labeling and long-term in-vivo observation simultaneously. In this work, we developed a high-precision infrared laser-evoked gene operator heat-shock system, which uses laser-induced CreERT2 combined with loxP-DsRedx-loxP-GFP reporter to achieve precise single-cell labeling and tracing. In vivo study indicated that this system can precisely label single cell in brain, muscle and hematopoietic system in zebrafish embryo. Using this system, we traced the hematopoietic potential of hemogenic endothelium (HE) in the posterior blood island (PBI) of zebrafish embryo and found that HEs in the PBI are heterogeneous, which contains at least myeloid unipotent and myeloid-lymphoid bipotent subtypes.
Animals begin life as a single cell that then divides to become a complex organism with many different types of cells. Every time a cell divides, each of its two daughter cells can either stay the same type as their parent or adopt a different identity. Once a cell acquires an identity, it usually cannot 'go back' and choose another. Eventually, this process will produce daughter cells with the identity of a specific tissue or organ and that cannot divide further. Multipotent cells are cells that can produce daughter cells with different identities, including other multipotent cells. These cells can usually give rise to different cell types in a specific organ, and generate more cells to replace any cells that die in that organ. Tracking the cells descended from a multipotent cell in a specific tissue can provide information about how the tissue develops. Hemogenic endothelium cells produce the multipotent cells that give rise to two types of white blood cells: myeloid cells and lymphoid cells. Myeloid cells include innate immune cells that protect the body from infection non-specifically; while lymphoid cells include T cells and B cells with receptors that detect specific bacteria or viruses. It remains unclear whether each of these two cell types originate from a single population of hemogenic endothelium cells or from two distinct subpopulations. He et al. have now developed a new optical technique to label a single hemogenic endothelium cell in a zebrafish and track the cell and its descendants. This method revealed that there are at least two distinct populations of hemogenic endothelium cells. One of them can give rise to both lymphoid and myeloid cells, while the other can only give rise to myeloid cells. These findings shed light on the mechanisms of blood formation, and potentially could provide useful tools to study the development of diseases such as leukemia. Additionally, the single-cell labeling technology He et al. have developed could be applied to study the development of other tissues and organs.
Assuntos
Linhagem da Célula , Microscopia Confocal , Análise de Célula Única/métodos , Peixe-Zebra , Animais , Análise de Célula Única/instrumentaçãoRESUMO
As nontechnical losses in power systems have recently become a global concern, electricity fraud detection models attracted increasing academic interest. The wide application of smart meters has offered more possibility to detecting fraud from user's consumption patterns. However, the performances of existing consumption-based electricity fraud detection models are still not satisfactory enough for practice, partly due to their limited ability to handle high-dimensional data. In this paper, a deep-learning-based model is developed for detecting electricity fraud in the advanced metering infrastructure, namely, the multitask feature extracting fraud detector (MFEFD). The deep architecture has brought MFEFD a powerful ability to handle high-dimensional input, through which consumption patterns inside load profiles can be effectively extracted. Another challenge is that the insufficiency of labeled data has restricted the generalization of existing models since they are mostly based on supervised learning and labeled data. MFEFD is trained in a semisupervised manner, in which multitask training was implemented to combine the supervised and unsupervised training, so that both the knowledge from unlabeled and labeled data can be made use of. Real-world-data-based case studies have demonstrated MFEFD's high detection performance, robustness, privacy preservation, and practicability.
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The resistances of magnesium alloys to wear, friction and corrosion can be effectively improved by depositing coatings on their surfaces. However, the coatings can also reduce the heat transfer from the coated components to the surroundings (e.g., coated cylinder bores for internal combustion of engine blocks). In this paper, nanostructured magnesium oxides were produced by plasma electrolytic oxidation (PEO) process on the magnesium alloy AJ62 under different current densities. The guarded comparative heat flow method was adopted to measure the thermal conductivities of such coatings which possess gradient nanoscale grain sizes. The aim of the paper is to explore how the current density in the PEO process affects the thermal conductivity of the nanostructured magnesium coatings. The experimental results show that, as the current density rises from 4 to 20 A/mm2, the thermal conductivity has a slight increase from 0.94 to 1.21 W/m x K, which is significantly smaller than that of the corresponding bulk magnesium oxide materials (29.4 W/m x K). This mostly attributed to the variation of the nanoscale grain sizes of the PEO coatings.