Detalhe da pesquisa
1.
SAMHD1 Promotes the Antiretroviral Adaptive Immune Response in Mice Exposed to Lipopolysaccharide.
J Immunol
; 208(2): 444-453, 2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34893529
2.
Elimination of Aicardi-Goutières syndrome protein SAMHD1 activates cellular innate immunity and suppresses SARS-CoV-2 replication.
J Biol Chem
; 298(3): 101635, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35085552
3.
Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J Biol Chem
; 297(4): 101170, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34492268
4.
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.
Nucleic Acids Res
; 48(4): 1886-1904, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31853544
5.
SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.
Proc Natl Acad Sci U S A
; 115(19): 4921-4926, 2018 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669924
6.
Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages.
Retrovirology
; 16(1): 29, 2019 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31655617
7.
A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.
J Virol
; 92(6)2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321329
8.
A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse.
J Biol Chem
; 292(3): 1068-1080, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27920203
9.
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease.
Mol Pharmacol
; 87(2): 323-37, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25477342
10.
MESH1 knockdown triggers proliferation arrest through TAZ repression.
Cell Death Dis
; 13(3): 221, 2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35273140
11.
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Mob DNA
; 9: 11, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610582
12.
Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1.
Cell Rep
; 24(4): 815-823, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044979
13.
Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.
Nat Commun
; 9(1): 2227, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884836
14.
The small-molecule 3G11 inhibits HIV-1 reverse transcription.
Chem Biol Drug Des
; 89(4): 608-618, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27748043
15.
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Cell Rep
; 20(8): 1921-1935, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28834754
16.
Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection.
Virology
; 487: 273-84, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26580513
17.
HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes.
Virology
; 499: 383-396, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27764728
18.
Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect.
Sci Rep
; 6: 31353, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27511536
19.
SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.
Virology
; 495: 92-100, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27183329
20.
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.
Sci Rep
; 6: 26616, 2016 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27229711