Detalhe da pesquisa
1.
A General Strategy for N-(Hetero)arylpiperidine Synthesis Using Zincke Imine Intermediates.
J Am Chem Soc
; 146(1): 936-945, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38153812
2.
Substituent and Solvent Effect Studies of N-Alkenylnitrone 4π Electrocyclizations.
Chemistry
; 29(30): e202300551, 2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840693
3.
Accessing Diverse Azole Carboxylic Acid Building Blocks via Mild C-H Carboxylation: Parallel, One-Pot Amide Couplings and Machine-Learning-Guided Substrate Scope Design.
J Am Chem Soc
; 144(50): 23115-23126, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36490321
4.
Mechanistic Investigations of the Asymmetric Hydrogenation of Enamides with Neutral Bis(phosphine) Cobalt Precatalysts.
J Am Chem Soc
; 144(34): 15764-15778, 2022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35951601
5.
Total Synthesis of Darobactin A.
J Am Chem Soc
; 144(31): 14026-14030, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35900216
6.
Scalable Asymmetric Synthesis of MK-8998, a T-Type Calcium Channel Antagonist.
J Org Chem
; 87(4): 2120-2128, 2022 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34582192
7.
Cobalt-Catalyzed Asymmetric Hydrogenation of α,ß-Unsaturated Carboxylic Acids by Homolytic H2 Cleavage.
J Am Chem Soc
; 142(11): 5272-5281, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064867
8.
Diastereoselective FeCl3·6H2O/NaBH4 Reduction of Oxime Ether for the Synthesis of ß-Lactamase Inhibitor Relebactam.
J Org Chem
; 85(2): 994-1000, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31850754
9.
Synthesis of a CGRP Receptor Antagonist via an Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine.
J Org Chem
; 84(12): 8006-8018, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31124362
10.
Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.
J Org Chem
; 84(8): 4780-4795, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30475616
11.
The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis.
Acc Chem Res
; 50(12): 2976-2985, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29172435
12.
Cobalt-Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences.
J Am Chem Soc
; 138(10): 3314-24, 2016 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26854359
13.
Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,ß-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation.
J Am Chem Soc
; 138(10): 3562-9, 2016 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26890979
14.
Enantioselective Synthesis of α-Methyl-ß-cyclopropyldihydrocinnamates.
J Org Chem
; 81(3): 824-30, 2016 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743694
15.
Catalytic, asymmetric, and stereodivergent synthesis of non-symmetric ß,ß-diaryl-α-amino acids.
J Am Chem Soc
; 137(2): 999-1006, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523503
16.
Double-asymmetric hydrogenation strategy for the reduction of 1,1-diaryl olefins applied to an improved synthesis of CuIPhEt, a C2-symmetric N-heterocyclic carbenoid.
J Org Chem
; 78(6): 2731-5, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383707
17.
Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods.
Chem Sci
; 12(26): 9031-9036, 2021 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34276931
18.
Ruthenium-Catalyzed Enantioselective Hydrogenation of Hydrazones.
Org Lett
; 22(19): 7562-7566, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946691
19.
Cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction.
Science
; 360(6391): 888-893, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29798879
20.
Practical High-Throughput Experimentation for Chemists.
ACS Med Chem Lett
; 8(6): 601-607, 2017 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28626518