Detalhe da pesquisa
1.
Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC.
Bioorg Med Chem Lett
; 68: 128718, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378251
2.
Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations.
Angew Chem Int Ed Engl
; 59(34): 14481-14489, 2020 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510788
3.
Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites.
J Med Chem
; 65(2): 1370-1383, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668706
4.
Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
Cancer Cell
; 37(1): 104-122.e12, 2020 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935369
5.
Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors.
ACS Med Chem Lett
; 10(11): 1549-1553, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749909
6.
Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor.
Cancer Discov
; 9(7): 926-943, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092401
7.
Thiamine attenuates hypoxia-induced cell death in cultured neonatal rat cardiomyocytes.
Mol Cells
; 18(2): 133-40, 2004 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-15528987