Detalhe da pesquisa
1.
Cross-species prophylactic efficacy of Sm-p80-based vaccine and intracellular localization of Sm-p80/Sm-p80 ortholog proteins during development in Schistosoma mansoni, Schistosoma japonicum, and Schistosoma haematobium.
Parasitol Res
; 116(11): 3175-3188, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29026995
2.
Immuno-evasive tactics by schistosomes identify an effective allergy preventative.
Exp Parasitol
; 153: 139-50, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25819297
3.
Use of an Sm-p80-based therapeutic vaccine to kill established adult schistosome parasites in chronically infected baboons.
J Infect Dis
; 209(12): 1929-40, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24436452
4.
Simultaneous priming with DNA encoding Sm-p80 and boosting with Sm-p80 protein confers protection against challenge infection with Schistosoma mansoni in mice.
Parasitol Res
; 113(3): 1195-200, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24452916
5.
Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon.
Parasitol Res
; 113(6): 2239-50, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24728521
6.
Establishing a single-sex controlled human Schistosoma mansoni infection model for Uganda: protocol for safety and dose-finding trial.
Immunother Adv
; 3(1): ltad010, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37538934
7.
Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic.
J Infect Dis
; 204(9): 1437-49, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21921206
8.
Schistosomiasis vaccines.
Hum Vaccin
; 7(11): 1192-7, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22048120
9.
Sm-p80-based DNA vaccine provides baboons with levels of protection against Schistosoma mansoni infection comparable to those achieved by the irradiated cercarial vaccine.
J Infect Dis
; 201(7): 1105-12, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20187746
10.
Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings.
Front Immunol
; 12: 635985, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33746974
11.
Testing of Schistosoma mansoni Vaccine Targets.
Methods Mol Biol
; 2151: 229-262, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32452009
12.
Elucidation of Cellular Responses in Non-human Primates With Chronic Schistosomiasis Followed by Praziquantel Treatment.
Front Cell Infect Microbiol
; 10: 57, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32154190
13.
Process Development of Sj-p80: A Low-Cost Transmission-Blocking Veterinary Vaccine for Asiatic Schistosomiasis.
Front Immunol
; 11: 578715, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33732227
14.
Chronic whipworm infection exacerbates Schistosoma mansoni egg-induced hepatopathology in non-human primates.
Parasit Vectors
; 13(1): 109, 2020 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32111243
15.
Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection.
Front Immunol
; 11: 1246, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32636844
16.
Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by the irradiated cercarial vaccine.
Parasitol Res
; 105(6): 1767-77, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19809833
17.
Schistosoma egg-induced liver pathology resolution by Sm-p80-based schistosomiasis vaccine in baboons.
Pathology
; 50(4): 442-449, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29739616
18.
Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models.
J Investig Med
; 66(8): 1124-1132, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29997146
19.
Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter.
Ann N Y Acad Sci
; 1425(1): 19-37, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29888790
20.
Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy.
Ann N Y Acad Sci
; 1425(1): 38-51, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30133707