Detalhe da pesquisa
1.
A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens.
Nat Methods
; 9(4): 363-6, 2012 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343343
2.
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical MatterâCompounds with Novel Mechanisms from High-Throughput Screening Profiles.
ACS Chem Biol
; 19(4): 938-952, 2024 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565185
3.
DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
ACS Chem Biol
; 17(6): 1401-1414, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508359
4.
Engineering digitizer circuits for chemical and genetic screens in human cells.
Nat Commun
; 12(1): 6150, 2021 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34686672
5.
Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma.
Mol Cancer Res
; 17(1): 199-211, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30201825
6.
Protein kinase C modulates the up-regulation of the pyrimidine biosynthetic complex, CAD, by MAP kinase.
Front Biosci
; 12: 3892-8, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17485345
7.
The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.
Mol Cell Biol
; 33(21): 4166-80, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23979597
8.
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.
Nat Cell Biol
; 14(3): 318-28, 2012 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344029
9.
Vigilance and validation: Keys to success in RNAi screening.
ACS Chem Biol
; 6(1): 47-60, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21142076
10.
A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies.
PLoS One
; 6(9): e25511, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21966537
11.
Protein kinase A phosphorylation of the multifunctional protein CAD antagonizes activation by the MAP kinase cascade.
Mol Cell Biochem
; 301(1-2): 69-81, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17206380
12.
Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD.
J Biol Chem
; 280(27): 25611-20, 2005 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15890648
13.
Autophosphorylation of the mammalian multifunctional protein that initiates de novo pyrimidine biosynthesis.
J Biol Chem
; 277(27): 24809-17, 2002 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-11986331
14.
Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells.
Int J Cancer
; 109(4): 491-8, 2004 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-14991569
15.
Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades.
J Biol Chem
; 277(18): 15745-51, 2002 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-11872754
16.
Cell cycle-dependent regulation of pyrimidine biosynthesis.
J Biol Chem
; 278(5): 3403-9, 2003 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12438317