Detalhe da pesquisa
1.
An open-source high-content analysis workflow for CFTR function measurements using the forskolin-induced swelling assay.
Bioinformatics
; 36(24): 5686-5694, 2021 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33367496
2.
Zebrafish optineurin: genomic organization and transcription regulation.
Genome
; 65(10): 513-523, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037528
3.
Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies.
Int J Mol Sci
; 23(1)2021 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008443
4.
Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9.
Int J Mol Sci
; 22(23)2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884866
5.
A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.
Biochim Biophys Acta Mol Cell Res
; 1865(2): 421-431, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29154949
6.
Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone.
Biochim Biophys Acta Mol Basis Dis
; 1864(1): 143-151, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993189
7.
Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis.
J Cyst Fibros
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749892
8.
Additive Potentiation of R334W-CFTR Function by Novel Small Molecules.
J Pers Med
; 13(1)2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36675763
9.
Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators.
Front Mol Biosci
; 10: 1155705, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37006619
10.
Advances in Preclinical In Vitro Models for the Translation of Precision Medicine for Cystic Fibrosis.
J Pers Med
; 12(8)2022 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36013270
11.
Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids.
Cells
; 11(15)2022 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35892592
12.
Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis.
J Mol Biol
; 434(5): 167436, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990652
13.
Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A.
Cells
; 11(1)2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35011698
14.
Personalized Medicine Based on Nasal Epithelial Cells: Comparative Studies with Rectal Biopsies and Intestinal Organoids.
J Pers Med
; 11(5)2021 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34065744
15.
Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis.
J Exp Pharmacol
; 13: 693-723, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34326672
16.
Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis.
Front Physiol
; 11: 604580, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33424627
17.
Mutant CFTR Drives TWIST1 mediated epithelial-mesenchymal transition.
Cell Death Dis
; 11(10): 920, 2020 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106471
18.
Characterization of the mechanism of action of RDR01752, a novel corrector of F508del-CFTR.
Biochem Pharmacol
; 180: 114133, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32628927
19.
Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G.
Biochim Biophys Acta Mol Basis Dis
; 1866(11): 165905, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730979
20.
Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids.
STAR Protoc
; 1(1): 100019, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33111074