Detalhe da pesquisa
1.
Targeting Biomolecular Condensation and Protein Aggregation against Cancer.
Chem Rev
; 123(14): 9094-9138, 2023 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379327
2.
Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain.
Biochemistry
; 62(1): 35-43, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36535020
3.
Anticancer Therapeutic Strategies Targeting p53 Aggregation.
Int J Mol Sci
; 23(19)2022 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36232329
4.
Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer.
FASEB J
; 34(1): 365-385, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914616
5.
Process intensification for the production of yellow fever virus-like particles as potential recombinant vaccine antigen.
Biotechnol Bioeng
; 118(9): 3581-3592, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34143442
6.
Biophysical characterization of p53 core domain aggregates.
Biochem J
; 477(1): 111-120, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841126
7.
p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells.
J Biol Chem
; 294(10): 3670-3682, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602570
8.
Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells.
J Biol Chem
; 294(24): 9430-9439, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31028175
9.
The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation.
J Biol Chem
; 294(52): 20054-20069, 2019 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748410
10.
Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy.
Molecules
; 25(15)2020 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32752302
11.
Anticancer Potential of Resveratrol, ß-Lapachone and Their Analogues.
Molecules
; 25(4)2020 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32085381
12.
Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer.
J Biol Chem
; 293(29): 11374-11387, 2018 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853637
13.
Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer.
Acc Chem Res
; 51(1): 181-190, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29260852
14.
Prion-like aggregation of mutant p53 in cancer.
Trends Biochem Sci
; 39(6): 260-7, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24775734
15.
Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.
J Biol Chem
; 292(22): 9345-9357, 2017 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420731
16.
Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion.
J Biol Chem
; 292(6): 2379-2394, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049727
17.
A hypothesis to reconcile the physical and chemical unfolding of proteins.
Proc Natl Acad Sci U S A
; 112(21): E2775-84, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964355
18.
The "Jekyll and Hyde" Actions of Nucleic Acids on the Prion-like Aggregation of Proteins.
J Biol Chem
; 291(30): 15482-90, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288413
19.
Regulation of Amyloid ß Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.
J Biol Chem
; 291(42): 21945-21955, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27563063
20.
Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target.
Molecules
; 22(6)2017 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28629161