Detalhe da pesquisa
1.
Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.
J Biol Chem
; 291(1): 342-54, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26504077
2.
Kinetically-defined component actions in gene repression.
PLoS Comput Biol
; 11(3): e1004122, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25816223
3.
A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.
Biochemistry
; 53(11): 1753-67, 2014 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24559102
4.
PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation.
J Biol Chem
; 288(1): 42-58, 2013 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23161582
5.
A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.
J Biol Chem
; 288(47): 34055-34072, 2013 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24097989
6.
Disruption of Ttll5/stamp gene (tubulin tyrosine ligase-like protein 5/SRC-1 and TIF2-associated modulatory protein gene) in male mice causes sperm malformation and infertility.
J Biol Chem
; 288(21): 15167-80, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23558686
7.
The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.
Crit Rev Toxicol
; 44 Suppl 3: 17-43, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070415
8.
Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation.
J Biol Chem
; 287(49): 40982-95, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23055525
9.
Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations.
J Biol Chem
; 287(53): 44546-60, 2012 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23132854
10.
A theoretical framework for gene induction and experimental comparisons.
Proc Natl Acad Sci U S A
; 107(15): 7107-12, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351279
11.
Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.
Biochemistry
; 50(3): 356-66, 2011 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21142156
12.
STAMP alters the growth of transformed and ovarian cancer cells.
BMC Cancer
; 10: 128, 2010 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20374646
13.
STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression.
Mol Cell Biol
; 27(4): 1467-85, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17116691
14.
What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.
Bioessays
; 30(8): 744-56, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18623071
15.
Dissecting transcriptional amplification by MYC.
Elife
; 92020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32715994
16.
Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction.
Mol Cell Endocrinol
; 299(2): 219-31, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19007848
17.
Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression.
Biochemistry
; 47(29): 7648-62, 2008 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18578507
18.
Differential modulation of glucocorticoid and progesterone receptor transactivation.
Mol Cell Endocrinol
; 283(1-2): 114-26, 2008 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18215457
19.
An Approach to Greater Specificity for Glucocorticoids.
Front Endocrinol (Lausanne)
; 9: 76, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29593646
20.
How much is enough? Modulation of dose-response curve for steroid receptor-regulated gene expression by changing concentrations of transcription factor.
Curr Top Med Chem
; 6(3): 271-85, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16515481