Detalhe da pesquisa
1.
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Nature
; 588(7836): 157-163, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33239784
2.
A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.
Blood
; 142(1): 90-105, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146239
3.
Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains.
Genes Dev
; 26(4): 344-9, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22345515
4.
Chromatin-modifying enzymes as modulators of reprogramming.
Nature
; 483(7391): 598-602, 2012 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22388813
5.
Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Blood
; 121(13): 2533-41, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23361907
6.
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Proc Natl Acad Sci U S A
; 109(13): 5028-33, 2012 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396593
7.
eXframe: reusable framework for storage, analysis and visualization of genomics experiments.
BMC Bioinformatics
; 12: 452, 2011 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22103807
8.
Dissecting microregulation of a master regulatory network.
BMC Genomics
; 9: 88, 2008 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18294391
9.
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms.
BMC Bioinformatics
; 8: 82, 2007 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17343765
10.
MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.
J Clin Invest
; 126(3): 997-1011, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26878175
11.
MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
J Clin Invest
; 126(4): 1438-50, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927674
12.
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Nat Med
; 21(4): 335-43, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25822366
13.
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.
Nat Commun
; 5: 3469, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24662245
14.
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Cancer Cell
; 26(6): 896-908, 2014 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25464900
15.
iCanPlot: visual exploration of high-throughput omics data using interactive Canvas plotting.
PLoS One
; 7(2): e31690, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393367
16.
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Cell Stem Cell
; 11(3): 429-39, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22958934
17.
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Cancer Cell
; 20(1): 66-78, 2011 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21741597
18.
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
Science
; 327(5973): 1650-3, 2010 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20339075
19.
MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.
Clin Cancer Res
; 16(7): 2122-30, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20332322
20.
Sensitivity analysis for reversal distance and breakpoint reuse in genome rearrangements.
Pac Symp Biocomput
; : 37-48, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229675