Detalhe da pesquisa
1.
Regulated control of gene therapies by drug-induced splicing.
Nature
; 596(7871): 291-295, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34321659
2.
Author Correction: Regulated control of gene therapies by drug-induced splicing.
Nature
; 602(7897): E25, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35105975
3.
SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.
Nat Chem Biol
; 11(7): 511-7, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030728
4.
Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy.
Proc Natl Acad Sci U S A
; 110(26): E2371-80, 2013 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23757500
5.
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
Res Sq
; 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585969
6.
Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.
Nat Chem Biol
; 12(4): 304, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26991088
7.
Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.
Nat Chem Biol
; 11(9): 741, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26284678
8.
An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion.
Nat Commun
; 13(1): 1150, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35241644
9.
Orally administered branaplam does not impact neurogenesis in juvenile mice, rats, and dogs.
Biol Open
; 10(10)2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34528068
10.
Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators.
J Med Chem
; 64(8): 4744-4761, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33822618
11.
Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease.
Neurology
; 96(5): e671-e683, 2021 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199433
12.
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
Neurology
; 96(18): e2296-e2312, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33827960
13.
Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study.
Lancet Neurol
; 20(9): 739-752, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34418401
14.
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth.
Neuron
; 35(2): 283-90, 2002 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-12160746
15.
PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration.
Nat Neurosci
; 7(3): 261-8, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14770187
16.
Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).
J Med Chem
; 61(24): 11021-11036, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30407821
17.
Synthetic transcription elongation factors license transcription across repressive chromatin.
Science
; 358(6370): 1617-1622, 2017 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29192133
18.
Identification of novel genes and pathways regulating SREBP transcriptional activity.
PLoS One
; 4(4): e5197, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19381295
19.
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
J Neurochem
; 102(4): 1151-61, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17488279
20.
P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp.
Nature
; 420(6911): 74-8, 2002 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12422217