Detalhe da pesquisa
1.
Computational methods in drug discovery.
Pharmacol Rev
; 66(1): 334-95, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24381236
2.
Protocols for Molecular Modeling with Rosetta3 and RosettaScripts.
Biochemistry
; 55(34): 4748-63, 2016 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27490953
3.
Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign.
J Comput Aided Mol Des
; 30(3): 209-17, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721261
4.
A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target.
PLoS Genet
; 9(2): e1003313, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468647
5.
Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.
J Biol Chem
; 289(9): 5846-59, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375409
6.
BCL::EMAS--enantioselective molecular asymmetry descriptor for 3D-QSAR.
Molecules
; 17(8): 9971-89, 2012 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22907158
7.
Mapping the Binding Sites of UDP and Prostaglandin E2 Glyceryl Ester in the Nucleotide Receptor P2Y6.
ChemMedChem
; 17(7): e202100683, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35034430
8.
PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection.
Genome Biol
; 21(1): 217, 2020 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32847609
9.
The Impact of Natural Selection on the Evolution and Function of Placentally Expressed Galectins.
Genome Biol Evol
; 11(9): 2574-2592, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504490
10.
PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors.
Clin Cancer Res
; 24(6): 1426-1435, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284706
11.
Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator.
J Med Chem
; 60(17): 7605-7612, 2017 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28795803
12.
Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6.
Sci Rep
; 7(1): 2380, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539604
13.
An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.
Cancer Discov
; 7(6): 575-585, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274957
14.
Discovery of Small-Molecule Modulators of the Human Y4 Receptor.
PLoS One
; 11(6): e0157146, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27294784
15.
Correction: PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors.
Clin Cancer Res
; 25(4): 1432, 2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770491
16.
Correction: An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.
Cancer Discov
; 9(2): 303, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737217
17.
Clozapine interaction with phosphatidyl inositol 3-kinase (PI3K)/insulin-signaling pathway in Caenorhabditis elegans.
Neuropsychopharmacology
; 34(8): 1968-78, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19322168
18.
The relevance of Caenorhabditis elegans genetics for understanding human psychiatric disease.
Harv Rev Psychiatry
; 19(4): 210-8, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21790269