Detalhe da pesquisa
1.
Pivekimab sunirine (IMGN632), a novel CD123-targeting antibody-drug conjugate, in relapsed or refractory acute myeloid leukaemia: a phase 1/2 study.
Lancet Oncol
; 25(3): 388-399, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423051
2.
Population pharmacokinetics of mirvetuximab soravtansine in patients with folate receptor-α positive ovarian cancer: The antibody-drug conjugate, payload and metabolite.
Br J Clin Pharmacol
; 90(2): 568-581, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872122
3.
The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models.
Haematologica
; 104(8): 1633-1639, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30733273
4.
Development of an FRα Companion Diagnostic Immunohistochemical Assay for Mirvetuximab Soravtansine.
Arch Pathol Lab Med
; 2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38282564
5.
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.
PLoS Pathog
; 6(11): e1001192, 2010 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21085614
6.
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes.
Cell Signal
; 20(7): 1267-74, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18424071
7.
Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells.
Clin Cancer Res
; 14(16): 5116-23, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18698029
8.
IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML.
Mol Cancer Ther
; 17(6): 1271-1279, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29588393
9.
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models.
Neoplasia
; 19(9): 661-671, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753442
10.
Conditional expression of MAP kinase phosphatase-2 protects against genotoxic stress-induced apoptosis by binding and selective dephosphorylation of nuclear activated c-jun N-terminal kinase.
Cell Signal
; 17(10): 1254-64, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16038800
11.
Disruption of two putative nuclear localization sequences is required for cytosolic localization of mitogen-activated protein kinase phosphatase-2.
Cell Signal
; 17(6): 709-16, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15722195
12.
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
Br J Pharmacol
; 145(4): 535-44, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15821758
13.
Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic.
Mol Cancer Ther
; 14(7): 1625-36, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25911688
14.
Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2.
Cell Signal
; 22(3): 357-65, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19843478
15.
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Cancer Res
; 70(13): 5213-9, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551059