Detalhe da pesquisa
1.
Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression.
J Biol Chem
; 300(4): 107146, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460939
2.
Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.
Mol Pharmacol
; 105(3): 213-223, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38182432
3.
Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control.
J Virol
; 97(4): e0016023, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36939350
4.
Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types.
Am J Physiol Regul Integr Comp Physiol
; 326(6): R515-R527, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38618911
5.
Ure(k)a! Sirtuins Regulate Mitochondria.
Cell
; 137(3): 404-6, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19410538
6.
Current Trends in Sirtuin Activator and Inhibitor Development.
Molecules
; 29(5)2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474697
7.
Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis.
Proteins
; 90(1): 282-298, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34414607
8.
Chemical Regulation of the Protein Quality Control E3 Ubiquitin Ligase C-Terminus of Hsc70 Interacting Protein (CHIP).
Chembiochem
; 23(6): e202100633, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061295
9.
Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants.
J Biol Chem
; 295(25): 8524-8536, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371394
10.
Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses.
Circ Res
; 125(12): 1087-1102, 2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625810
11.
ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces.
BMC Bioinformatics
; 21(1): 186, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32410570
12.
Development of activity-based probes for the protein deacylase Sirt1.
Bioorg Chem
; 104: 104232, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911193
13.
Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1.
J Biol Chem
; 293(14): 5345-5359, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440272
14.
Comparative and integrative metabolomics reveal that S-nitrosation inhibits physiologically relevant metabolic enzymes.
J Biol Chem
; 293(17): 6282-6296, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483187
15.
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction.
Mol Cell
; 41(2): 139-49, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21255725
16.
Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein-Detected NMR Spectroscopy.
Chembiochem
; 19(5): 448-458, 2018 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29239081
17.
Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.
Biochemistry
; 56(41): 5485-5495, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945351
18.
Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation.
J Biol Chem
; 291(49): 25398-25410, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756843
19.
Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases.
Nitric Oxide
; 63: 52-60, 2017 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720836
20.
A multi-level modeling approach examining PTSD symptom reduction during prolonged exposure therapy: moderating effects of number of trauma types experienced, having an HIV-related index trauma, and years since HIV diagnosis among HIV-positive adults.
AIDS Care
; 29(11): 1391-1398, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28266223