Detalhe da pesquisa
1.
HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia.
Mol Cell
; 82(4): 833-851.e11, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35180428
2.
Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient ß-catenin/Hoxa9/Prmt1 axis.
Blood
; 143(16): 1586-1598, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38211335
3.
Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML.
Blood
; 142(23): 2002-2015, 2023 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738460
4.
Therapeutic Opportunities of Targeting Canonical and Noncanonical PcG/TrxG Functions in Acute Myeloid Leukemia.
Annu Rev Genomics Hum Genet
; 22: 103-125, 2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33929894
5.
Transcriptional memory of cells of origin overrides ß-catenin requirement of MLL cancer stem cells.
EMBO J
; 36(21): 3139-3155, 2017 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28978671
6.
Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation.
EMBO J
; 32(7): 982-95, 2013 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23455154
7.
Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.
Blood
; 125(25): 3928-36, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940713
8.
Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia.
Blood
; 123(16): 2518-29, 2014 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591202
9.
Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement.
FASEB J
; 29(4): 1505-15, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550471
10.
MLL-AF4, a double-edged sword for iPSC respecification into HSPCs.
Proc Natl Acad Sci U S A
; 115(9): 1964-1966, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29444865
11.
DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance.
Chromosoma
; 123(6): 545-61, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25112726
12.
Recruitment of RXR by homotetrameric RARalpha fusion proteins is essential for transformation.
Cancer Cell
; 12(1): 36-51, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17613435
13.
Protein arginine-methyltransferase-dependent oncogenesis.
Nat Cell Biol
; 9(10): 1208-15, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17891136
14.
Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells.
Cancer Cell
; 9(2): 95-108, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16473277
15.
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Nat Cancer
; 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637657
16.
Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}.
Blood
; 115(3): 643-52, 2010 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19965660
17.
Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia.
Haematologica
; 102(8): e300-e304, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28522575
18.
Transforming activity of AML1-ETO is independent of CBFbeta and ETO interaction but requires formation of homo-oligomeric complexes.
Proc Natl Acad Sci U S A
; 106(8): 2853-8, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19202074
19.
A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify®.
Oncogene
; 41(48): 5160-5175, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271030
20.
Reconstruction of Human AML Using Functionally and Immunophenotypically Defined Human Haematopoietic Stem and Progenitor Cells as Targeted Populations.
Bio Protoc
; 11(24): e4262, 2021 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35087921