Detalhe da pesquisa
1.
Phenotypic Evaluation of Nucleoside Analogues against Trypanosoma cruzi Infection: In Vitro and In Vivo Approaches.
Molecules
; 27(22)2022 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36432189
2.
In Vitro and In Vivo Evaluation of an Adamantyl-Based Phenyl Sulfonyl Acetamide against Cutaneous Leishmaniasis Models of Leishmania amazonensis.
Antimicrob Agents Chemother
; 64(12)2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32928731
3.
New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors.
Bioorg Med Chem
; 27(14): 3061-3069, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176565
4.
In Vitro, In Silico, and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203486
5.
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
Antimicrob Agents Chemother
; 60(2): 1058-66, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26643331
6.
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.
Parasitology
; 143(11): 1469-78, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312370
7.
Different Therapeutic Outcomes of Benznidazole and VNI Treatments in Different Genders in Mouse Experimental Models of Trypanosoma cruzi Infection.
Antimicrob Agents Chemother
; 59(12): 7564-70, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416857
8.
In vitro and in vivo biological effects of novel arylimidamide derivatives against Trypanosoma cruzi.
Antimicrob Agents Chemother
; 58(7): 3720-6, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24752263
9.
Norfloxacin Zn(II)-based complexes: acid base ionization constant determination, DNA and albumin binding properties and the biological effect against Trypanosoma cruzi.
Biometals
; 26(5): 813-25, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897315
10.
N6-modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation.
Eur J Med Chem
; 231: 114165, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35144125
11.
In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi.
J Antimicrob Chemother
; 64(4): 747-50, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19671588
12.
Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro.
Exp Parasitol
; 123(1): 73-80, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19520077
13.
Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies.
Mem Inst Oswaldo Cruz
; 104 Suppl 1: 301-10, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19753489
14.
Discovery of Pyrrolo[2,3-b]pyridine (1,7-Dideazapurine) Nucleoside Analogues as Anti-Trypanosoma cruzi Agents.
J Med Chem
; 62(19): 8847-8865, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495177
15.
In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.
Antimicrob Agents Chemother
; 52(9): 3307-14, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18625779
16.
Sterol 14α-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae.
J Med Chem
; 61(23): 10910-10921, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30451500
17.
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.
ChemMedChem
; 13(12): 1246-1259, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29624912
18.
Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro".
Biochem Pharmacol
; 73(12): 1939-46, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17462605
19.
Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity.
Bioinorg Chem Appl
; 2016: 5027404, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924953
20.
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.
Eur J Med Chem
; 115: 295-310, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017556