Detalhe da pesquisa
1.
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aß pathology in Alzheimer's disease models.
Acta Pharmacol Sin
; 45(5): 900-913, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38225393
2.
TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation.
J Neuroinflammation
; 20(1): 21, 2023 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732771
3.
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Acta Pharmacol Sin
; 43(5): 1251-1263, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417577
4.
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
Acta Pharmacol Sin
; 43(10): 2511-2526, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217810
5.
Neuroprotective Natural Products for the Treatment of Parkinson's Disease by Targeting the Autophagy-Lysosome Pathway: A Systematic Review.
Phytother Res
; 31(8): 1119-1127, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28504367
6.
Neurogenic Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 18(2)2017 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28134846
7.
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
J Proteome Res
; 14(1): 467-78, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25271123
8.
PPARÉ Ligand Caudatin Improves Cognitive Functions and Mitigates Alzheimer's Disease Defects By Inducing Autophagy in Mice Models.
J Neuroimmune Pharmacol
; 18(3): 509-528, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37682502
9.
An autoimmunized mouse model recapitulates key features in the pathogenesis of Sjögren's syndrome.
Int Immunol
; 23(10): 613-24, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21846814
10.
Herbal remedies supply a novel prospect for the treatment of atherosclerosis: a review of current mechanism studies.
Phytother Res
; 26(2): 159-67, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21928391
11.
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition.
Phytomedicine
; 96: 153887, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34936968
12.
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.
Redox Biol
; 51: 102280, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286997
13.
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer's disease therapy.
Front Mol Biosci
; 9: 1030534, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36387280
14.
Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells.
Phytother Res
; 25(3): 435-43, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20740476
15.
Transcription factor EB: an emerging drug target for neurodegenerative disorders.
Drug Discov Today
; 26(1): 164-172, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33099023
16.
Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).
Autophagy
; 17(11): 3833-3847, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33622188
17.
Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review.
Biomed Pharmacother
; 133: 110968, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189067
18.
Qingyangshen mitigates amyloid-ß and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease.
Phytomedicine
; 91: 153648, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34332287
19.
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation.
Autophagy
; 17(5): 1112-1130, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32543313
20.
A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38.
Redox Biol
; 32: 101445, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037305