Detalhe da pesquisa
1.
From structure to mechanism-understanding initiation of DNA replication.
Genes Dev
; 31(11): 1073-1088, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28717046
2.
Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc Natl Acad Sci U S A
; 117(30): 17747-17756, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669428
3.
Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.
Genes Dev
; 28(20): 2291-303, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25319829
4.
A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.
Genes Dev
; 28(15): 1653-66, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25085418
5.
Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.
Mol Biol Evol
; 37(7): 1986-2001, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32145025
6.
An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
Mol Cell
; 50(4): 577-88, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603117
7.
An integrated workflow for crosslinking mass spectrometry.
Mol Syst Biol
; 15(9): e8994, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31556486
8.
Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Proc Natl Acad Sci U S A
; 114(45): E9529-E9538, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29078375
9.
Chromosomal Sil system contributes to silver resistance in E. coli ATCC 8739.
Biometals
; 31(6): 1101-1114, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30284644
10.
A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.
Nucleic Acids Res
; 43(21): 10238-50, 2015 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338774
11.
Helicase loading: how to build a MCM2-7 double-hexamer.
Semin Cell Dev Biol
; 30: 104-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637008
12.
Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.
Diabetologia
; 59(4): 776-84, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26739816
13.
Switch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated.
Chromosoma
; 124(1): 13-26, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25308420
14.
The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.
Nucleic Acids Res
; 42(4): 2257-69, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24234446
15.
In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
Nucleic Acids Res
; 41(5): 3162-72, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23376927
16.
Pre-RNA splicing in metabolic homeostasis and liver disease.
Trends Endocrinol Metab
; 34(12): 823-837, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37673766
17.
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Proc Natl Acad Sci U S A
; 106(48): 20240-5, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19910535
18.
The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer.
Nat Commun
; 13(1): 2915, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614055
19.
The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae.
Proc Natl Acad Sci U S A
; 105(30): 10326-31, 2008 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18647841
20.
The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun
; 12(1): 3883, 2021 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162887