Detalhe da pesquisa
1.
Genetic risk accentuates dietary effects on hepatic steatosis, inflammation and fibrosis in a population-based cohort.
J Hepatol
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582304
2.
PNPLA3 Genotype and Diabetes Identify Patients With Nonalcoholic Fatty Liver Disease at High Risk of Incident Cirrhosis.
Gastroenterology
; 164(6): 966-977.e17, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36758837
3.
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.
Hum Mol Genet
; 30(15): 1443-1456, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856023
4.
A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts.
J Hepatol
; 79(5): 1226-1235, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567366
5.
Polygenic Risk Prediction in Diverticulitis.
Ann Surg
; 277(6): e1262-e1268, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35876359
6.
Perturbation of TM6SF2 Expression Alters Lipid Metabolism in a Human Liver Cell Line.
Int J Mol Sci
; 22(18)2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34575933
7.
Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.
Hum Mol Genet
; 27(9): 1664-1674, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29481666
8.
PNPLA3 Risk Allele Association With ALT Response to Semaglutide Treatment.
Gastroenterology
; 166(3): 515-517.e2, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972824
9.
17-Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease.
Hepatology
; 69(4): 1504-1519, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30415504
10.
Genetic variants that associate with cirrhosis have pleiotropic effects on human traits.
Liver Int
; 40(2): 405-415, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31815349
11.
Independent markers of nonalcoholic fatty liver disease in a gentrifying population-based Chinese cohort.
Diabetes Metab Res Rev
; 35(5): e3156, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30892820
12.
Recent Advances in Human Genetics and Epigenetics of Adiposity: Pathway to Precision Medicine?
Gastroenterology
; 152(7): 1695-1706, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28214526
13.
ALDH1A1 Expression Is Enriched in Early-Onset Colorectal Cancers.
Gastroenterology
; 163(6): 1679-1681.e1, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985512
14.
FTO genotype is associated with phenotypic variability of body mass index.
Nature
; 490(7419): 267-72, 2012 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982992
15.
Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns.
J Lipid Res
; 58(7): 1471-1481, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539357
16.
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity.
Hum Mol Genet
; 24(23): 6849-60, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26376864
17.
Metabolic and genetic contributions to NAFLD: Really distinct and homogeneous?
J Hepatol
; 76(3): 498-500, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34979132
18.
Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans.
J Hum Genet
; 62(2): 175-184, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535031
19.
Nonalcoholic fatty liver disease and vascular function: cross-sectional analysis in the Framingham heart study.
Arterioscler Thromb Vasc Biol
; 35(5): 1284-91, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25745056
20.
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature
; 467(7317): 832-8, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20881960