Detalhe da pesquisa
1.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol Cell
; 83(15): 2753-2767.e10, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478846
2.
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML.
Blood
; 143(15): 1513-1527, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096371
3.
Small-molecule-induced polymerization triggers degradation of BCL6.
Nature
; 588(7836): 164-168, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208943
4.
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.
Nature
; 585(7824): 293-297, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32494016
5.
High-dose melphalan treatment significantly increases mutational burden at relapse in multiple myeloma.
Blood
; 141(14): 1724-1736, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603186
6.
PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.
Blood
; 142(24): 2079-2091, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595362
7.
Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms.
Blood
; 140(16): 1753-1763, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512188
8.
Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Blood
; 139(3): 357-368, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34855941
9.
Modeling and targeting of erythroleukemia by hematopoietic genome editing.
Blood
; 137(12): 1628-1640, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512458
10.
Quality of life, psychological distress, and prognostic perceptions in patients with multiple myeloma.
Cancer
; 128(10): 1996-2004, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167125
11.
Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis.
Blood
; 136(26): 3051-3055, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32961550
12.
Gait speed, survival, and recommended treatment intensity in older adults with blood cancer requiring treatment.
Cancer
; 127(6): 875-883, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33237587
13.
Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs.
Blood
; 134(2): 160-170, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31043423
14.
Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy.
Am J Hematol
; 95(3): 245-250, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31804723
15.
Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19.
Blood
; 140(18): 1993-1997, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36096050
16.
A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.
Am J Hematol
; 93(2): 254-261, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29119643
17.
Chromatin-dependent binding of the S. cerevisiae HMGB protein Nhp6A affects nucleosome dynamics and transcription.
Genes Dev
; 24(18): 2031-42, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20844014
18.
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.
Mol Cell
; 33(4): 417-27, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19250903
19.
Differential and limited expression of mutant alleles in multiple myeloma.
Blood
; 124(20): 3110-7, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25237203
20.
A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade.
Haematologica
; 106(2): 651-654, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054119