Detalhe da pesquisa
1.
NMR characterization and ligand binding site of the stem loop 2 motif (s2m) from the Delta variant of SARS-CoV-2.
RNA
; 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565242
2.
Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.
Chemistry
; 29(23): e202203967, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36799129
3.
The COVID19-NMR Consortium: A Public Report on the Impact of this New Global Collaboration.
Angew Chem Int Ed Engl
; 62(14): e202217171, 2023 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36748955
4.
19 F NMR-Based Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and Protein Counter-Screens.
Chembiochem
; 22(2): 423-433, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32794266
5.
Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS-CoV-2 Genome.
Angew Chem Int Ed Engl
; 60(35): 19191-19200, 2021 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161644
6.
NMR quality control of fragment libraries for screening.
J Biomol NMR
; 74(10-11): 555-563, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32533387
7.
Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation.
Nucleic Acids Res
; 46(20): 10917-10929, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30124944
8.
The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture.
J Biol Chem
; 293(30): 11823-11836, 2018 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884774
9.
Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor.
Chemistry
; 24(31): 7861-7865, 2018 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29656465
10.
Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J Biol Chem
; 290(26): 16415-30, 2015 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25979334
11.
Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies.
Chembiochem
; 17(23): 2257-2263, 2016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27685543
12.
NMR 1H,19F-based screening of the four stem-looped structure 5_SL1-SL4 located in the 5'-untranslated region of SARS-CoV 2 RNA.
RSC Med Chem
; 15(1): 165-177, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38283228
13.
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection.
RSC Med Chem
; 15(4): 1176-1188, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665834
14.
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
ACS Chem Biol
; 19(2): 563-574, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232960
15.
The apo-structure of the low molecular weight protein-tyrosine phosphatase A (MptpA) from Mycobacterium tuberculosis allows for better target-specific drug development.
J Biol Chem
; 287(41): 34569-82, 2012 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22888002
16.
MOTOR: model assisted software for NMR structure determination.
Proteins
; 81(11): 2007-22, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23852655
17.
Targeting EPHA2 with Kinase Inhibitors in Colorectal Cancer.
ChemMedChem
; 18(23): e202300420, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37736700
18.
Crystal structure of the CoV-Y domain of SARS-CoV-2 nonstructural protein 3.
Sci Rep
; 13(1): 2890, 2023 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36801935
19.
Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTnI).
Biosensors (Basel)
; 13(4)2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37185530
20.
NMR resonance assignment of a fibroblast growth factor 8 splicing isoform b.
Biomol NMR Assign
; 17(1): 135-142, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118562