Gastrointestinal release site for delayed release and gelatin capsules in healthy dogs.

Gelatin capsules deliver their contents to the stomach, while delayed-release (DR) capsules are designed to allow delivery to the small intestine. This study evaluated the gastrointestinal release site of DR capsules in six healthy adult dogs compared to gelatin capsules. Both gelatin and DR capsules were filled with barium-impregnated polyethylene spheres (BIPS™), and following enteral administration, release site was assessed using abdominal radiographs at baseline, immediately after ingestion, 15 min post-ingestion, 30 min post-ingestion, and then every 30 min thereafter. The evaluated phases included fasted conditions (phase 1, n = 6), increased meal size (phase 2, n = 2), double encapsulation (phase 3, n = 2), and altered capsule size (phase 4, n = 1). The released site was the stomach in all phases for both capsule types. In phase 1, DR capsules had a significantly prolonged time (median 60 min, range 60-90) to release BIPS™ compared to gelatin capsules (15 min, range 15-30; p = .03). In phase 2 (full meal size), 3 (double encapsulation), and 4 (smaller capsule size) pilot studies, release time was prolonged but still occurred in the stomach. This is similar to the release site for gelatin capsules but differs from the release site for DR capsules in people. This has implications for pharmacologic outcomes for products that are affected by gastric physiology (e.g. fecal microbiota transplantation). Based on this pilot data, clinicians and researchers should not assume DR capsules will allow for intestinal delivery of contents in dogs. Future studies should be conducted on larger and varied populations of dogs.

Why do people share memories online? An examination of the motives and characteristics of social media users.

ABSTRACTSocial media has become one of the most powerful and ubiquitous means by which individuals curate and share their life stories with the world at large. Not surprisingly then, researchers have started to examine the reasons why individuals post personal memories on social media and said individuals' characteristics. Across two studies, we extended this line of research by further testing the Purposes of Online Memory Sharing Scale (POMSS) and its subscales: self, social, therapeutic and directive. Additionally, we examined which of these motives led college students (Study 1) and adults of a community sample (Study 2) to post personal memories on social media and whether said motives were associated with the individuals' psychological characteristics. Overall, the results revealed that emerging adults and older adults posted personal experiences on social media primarily for social reasons. We also found that extraversion, disclosure and social media usage predicted each of the motives for posting personal experiences on social media. In addition, individuals who were more lonely and who had lower self-esteem were more likely to post personal experiences on social media for therapeutic reasons. We discuss these results in terms of their implications towards understanding the mnemonic consequences associated with social media use.

Fluctuating confidence: the dynamic consequences of true/false affirmatives and denials on how a listener appraises their personal past.

The present study examined the mnemonic consequences of true/false denials and affirmatives on how a listener appraises their personal past. To this end, participants (listeners) rated the extent to which they were confident certain events occurred during their childhood. They rated these events both before and after a confederate (speaker) denied or affirmed the occurrence of four different childhood events each, for a total of eight "rehearsed" events. For each set (denials and affirmatives) of events, half were true and half were false. In turn, this created four types of events (two each): true denials, true affirmatives, false denials, and false affirmatives. Additionally, half of the participants were told that the speaker was provided independent information about the veracity of the event's occurrence ("expert" condition). Overall, listeners were less confident in the occurrence of false denial events, but more so when they believed the speaker to be more knowledgeable of the listeners memories, more confident in false affirmative events and, counter intuitively, more confident in the occurrence of true denial events. These results underscore the importance of a nuanced approach to the mnemonic consequences of true and false denials and affirmations in the course of social interactions.

Alexithymia impairs the cognitive control of negative material while facilitating the recall of neutral material in both younger and older adults.

We investigated the moderating impact of the personality construct alexithymia on the ability of younger and older adults to control the recall of negative and neutral material. We conducted two experiments using the directed forgetting paradigm with younger and older adults. Participants studied negative (Experiment 1) or neutral (Experiment 2) words. Participants were instructed to forget the first half and remember the second half of an entire list of words. Overall, we found that alexithymia impairs the ability of both younger and older adults to cognitively control negative material (through both recall and inhibition). The "externally oriented thinking" factor of alexithymia appears to play a particularly pertinent role in terms of inhibiting negative material. Furthermore, older adults recalled fewer sought after negative items, but this was not evident in terms of inhibition. In contrast, only age (older adults) negatively impacted the recall of sought after neutral items. Interestingly, alexithymia had the opposite effect: the "difficulty in identifying emotions" factor of alexithymia was associated with an increased recall of neutral items. We discuss these results in terms of alexithymia and its impact on cognitive control.

Justifying atrocities: the effect of moral-disengagement strategies on socially shared retrieval-induced forgetting.

A burgeoning literature has established that exposure to atrocities committed by in-group members triggers moral-disengagement strategies. There is little research, however, on how such moral disengagement affects the degree to which conversations shape people's memories of the atrocities and subsequent justifications for those atrocities. We built on the finding that a speaker's selective recounting of past events can result in retrieval-induced forgetting of related, unretrieved memories for both the speaker and the listener. In the present study, we investigated whether American participants listening to the selective remembering of atrocities committed by American soldiers (in-group condition) or Afghan soldiers (out-group condition) resulted in the retrieval-induced forgetting of unmentioned justifications. Consistent with a motivated-recall account, results showed that the way people's memories are shaped by selective discussions of atrocities depends on group-membership status.

Remembering President Barack Obama's inauguration and the landing of US Airways Flight 1549: a comparison of the predictors of autobiographical and event memory.

We examined and compared the predictors of autobiographical memory (AM) consistency and event memory accuracy across two publicly documented yet disparate public events: the inauguration of Barack Obama as the 44th president of the United States on January 20th 2009, and the emergency landing of US Airways Flight 1549, off the coast of Manhattan, on January 15th 2009. We tracked autobiographical and event memories for both events, with assessments taking place within 2½ weeks of both events (Survey 1), and again between 3½ and 4 months after both events (Survey 2). In a series of stepwise regressions we found that the psychological variables of recalled emotional intensity and personal importance/centrality predicted AM consistency and event memory accuracy for the inauguration. Conversely, the rehearsal variables of covert rehearsal and media attention predicted, respectively, AM consistency and event memory accuracy for the plane landing. We conclude from these findings that different factors may underlie autobiographical and event memory for personally and culturally significant events (e.g., the inauguration), relative to noteworthy, yet less culturally significant, events (e.g., the plane landing).

Building consensus about the past: schema consistency and convergence in socially shared retrieval-induced forgetting.

A large body of literature on "within-individual retrieval-induced forgetting" (WI-RIF; Anderson, Bjork, & Bjork, 1994) shows that repeatedly retrieving some items, while not retrieving other related items, facilitates later recall of the practised items, but inhibits later recall of the non-practised related items. This robust effect has recently been extended to "socially shared retrieval-induced forgetting" (SS-RIF; Cuc, Koppel, & Hirst, 2007). People who merely listen to a speaker retrieving some, but not other, items-even people participating as speakers or listeners in conversations-show the same facilitation and inhibition. We replicated and extended the SS-RIF effect with a structured story (Experiment 1) and in a free-flowing conversation about the story (Experiment 2). Specifically, we explored (1) the degree to which participants subsequently form a coherent "collective memory" of the story and (2) whether schema consistency of the target information influences both WI-RIF and SS-RIF. In both experiments, speakers and listeners showed RIF (that is, WI-RIF and SS-RIF, respectively), irrespective of the schema consistency of the story material. On final recall, speakers and listeners described similar renderings of the story. We discuss these findings in terms of the role of "silences" in the formation of collective memories.

From Conversations to Digital Communication: The Mnemonic Consequences of Consuming and Producing Information via Social Media.

Social media has become one of the most powerful and ubiquitous means by which individuals curate, share, and communicate information with their friends, family, and the world at large. Indeed, 90% of the American adolescents are active social media users, as well as 65% of American adults (Perrin, 2015; see also Duggan & Brenner, 2013). Despite this, psychologists are only beginning to understand the mnemonic consequences associated with social media use. In this article, we will distill this nascent literature by focusing on two primary factors: the type of information (personal vs. public) and the role (producer vs. consumer) individuals play when engaging with social media. In particular, we will highlight research examining induced forgetting for personal information as well as false memories and truthiness for public information. We will end by providing some tentative conclusions and a discussion of areas in need of additional research that will provide a more holistic understanding of the mnemonic consequences associated with social media use.

Editors' Introduction: Remembering With Others: Conversational Dynamics and Mnemonic Outcomes.

Remembering the past through conversations with others is a uniquely human endeavor. Conversational remembering consists of specific dynamics and can lead to mnemonic outcomes. While conversational dynamics refer to the interactive processes (e.g., the roles speakers and listeners may undertake during the conversation) shaping collaborative remembering, conversational outcomes are about the mnemonic and functional consequences (e.g., forging social bonds) of those processes. Thus, the aim of the present article is to introduce the reader to key concepts and paradigms that have been rigorously developed to empirically investigate the dynamics and outcomes of conversational remembering in cognitive research. The collected review and empirical articles gathered in this topic provide the state-of-the-art in the field.

The Mnemonic Consequences of Jurors' Selective Retrieval During Deliberation.

The jury is a defining component of the American criminal justice system, and the courts largely assume that the collaborative nature of jury deliberations will enhance jurors' memory for important trial information. However, research suggests that this kind of collaboration, although sometimes improving memory, can also lead to incomplete and inaccurate "collective" memories. The present research examines whether jury deliberations, where individuals collaboratively recall and discuss trial evidence to render unanimous verdicts, might shape jurors' memories through the robust phenomena of Within-Individual and Socially Shared Retrieval-Induced Forgetting (WI-RIF and SS-RIF, respectively). The results revealed no WI-RIF or SS-RIF. However, we did find evidence in the direction of Within-Individual and Socially-shared Retrieval Induced Facilitation (WI-RIFA and SS-RIFA, respectively) in speakers' and listeners' narrative and open-ended recall of evidentiary details. The present results are discussed in terms of whether jurors' goals during deliberation and the deliberation structure (e.g., six or more discussants) protect against forgetting, or whether possible methodological issues (e.g., the vast amount of information presented) eliminated WI-RIF and SS-RIF and, in turn, make drawing conclusions surrounding the mnemonic impact of jury deliberation difficult. Regardless, the present results suggest jury deliberations are quite limited in terms of how much evidence is actually discussed compared to the total of what could be discussed, and our methodology provides an ecologically valid baseline for future research to better understand the mnemonic consequences associated with jury deliberations and, in turn, jury decision making.

Induced forgetting and reduced confidence in our personal past? The consequences of selectively retrieving emotional autobiographical memories.

People build their sense of self, in part, through their memories of their personal past. What is striking about these personal memories is that, in many instances, they are inaccurate, yet confidently held. Most researchers assume that confidence ratings are based, in large part, on the memory's mnemonic features. That is, the more vivid or detailed the memory, the higher the confidence people have in its accuracy. However, we explore a heretofore underappreciated source on which confidence ratings may be based: the accessibility of memories as a result of selective retrieval. To explore this possibility, we use Anderson, Bjork, and Bjork's retrieval-induced forgetting (RIF) paradigm with emotional (positive and negative) autobiographical memories. We found the standard RIF effect for memory recall across emotional valence. That is, selective retrieval of emotional autobiographical memories induced forgetting of related, but not retrieved emotional autobiographical memories compared to the baseline. More interestingly, we found that the confidence ratings for positive memories mirrored the RIF pattern: decreased confidence for related, unpracticed autobiographical memories relative to the baseline. For negative memories, we found the opposite pattern: increased confidence for both practiced autobiographical memories and related, unpracticed autobiographical memories. We discuss these results in terms of accessibility, the diverging mnemonic consequences of selectively retrieving positive and negative autobiographical memories and personal identity.

Forgetting our personal past: socially shared retrieval-induced forgetting of autobiographical memories.

People often talk to others about their personal past. These discussions are inherently selective. Selective retrieval of memories in the course of a conversation may induce forgetting of unmentioned but related memories for both speakers and listeners (Cuc, Koppel, & Hirst, 2007). Cuc et al. (2007) defined the forgetting on the part of the speaker as within-individual retrieval-induced forgetting (WI-RIF) and the forgetting on the part of the listener as socially shared retrieval-induced forgetting (SS-RIF). However, if the forgetting associated with WI-RIF and SS-RIF is to be taken seriously as a mechanism that shapes both individual and shared memories, this mechanism must be demonstrated with meaningful material and in ecologically valid groups. In our first 2 experiments we extended SS-RIF from unemotional, experimenter-contrived material to the emotional and unemotional autobiographical memories of strangers (Experiment 1) and intimate couples (Experiment 2) when merely overhearing the speaker selectively practice memories. We then extended these results to the context of a free-flowing conversation (Experiments 3 and 4). In all 4 experiments we found WI-RIF and SS-RIF regardless of the emotional valence or individual ownership of the memories. We discuss our findings in terms of the role of conversational silence in shaping both our personal and shared pasts.

Toward a Science of Silence: The Consequences of Leaving a Memory Unsaid.

Silence about the past permeates acts of remembering, with marked mnemonic consequences. Mnemonic silence-the absence of expressing a memory-is public in nature and is embedded within communicative acts, such as conversations. As such, silence has the potential to affect both speakers-the source of the silence-and listeners-those attending to the speaker. Although the topic of silence is widely discussed, it is rarely mentioned in the empirical literature on memory. Three factors are employed to classify silence into different types: whether a silence is accompanied by covert remembering, whether the silence is intentional or unintentional, and whether the silenced memory is related or unrelated to the memories emerging in a conversation. These factors appear to be critical when considering the mnemonic consequences. Moreover, the influence of silence on memory varies between speaker and listener. Although rarely mentioned, recent empirical research on memory clearly has a bearing on a topic of such general interest as silence.