Detalhe da pesquisa
1.
Fibroblast growth factor receptor 1 inhibition suppresses pancreatic cancer chemoresistance and chemotherapy-driven aggressiveness.
Drug Resist Updat
; 73: 101064, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38387284
2.
Comparative Proteomic Analysis Identifies Key Metabolic Regulators of Gemcitabine Resistance in Pancreatic Cancer.
Mol Cell Proteomics
; 21(10): 100409, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084875
3.
Species-Deconvolved Proteomics for In Situ Investigation of Tumor-Stroma Interactions after Treatment of Pancreatic Cancer Patient-Derived Xenografts with Combined Gemcitabine and Paclitaxel.
J Proteome Res
; 22(7): 2436-2449, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311110
4.
Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway.
J Proteome Res
; 22(12): 3780-3792, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906173
5.
Synergistic Pharmacodynamic Effects of Gemcitabine and Fibroblast Growth Factor Receptor Inhibitors on Pancreatic Cancer Cell Cycle Kinetics and Proliferation.
J Pharmacol Exp Ther
; 377(3): 370-384, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753538
6.
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer.
Br J Cancer
; 123(10): 1502-1512, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913288
7.
Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells.
BMC Cancer
; 20(1): 1024, 2020 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097020
8.
Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-Scale, Ion-Current-Based Quantitative Proteomics (IonStar).
Mol Cell Proteomics
; 17(4): 655-671, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358341
9.
Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients.
Int J Mol Sci
; 21(3)2020 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024004
10.
Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer.
Pharm Res
; 35(5): 95, 2018 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29536232
11.
Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts.
J Pharmacokinet Pharmacodyn
; 45(5): 733-746, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069744
12.
Flow arrest intra-arterial delivery of small TAT-decorated and neutral micelles to gliomas.
J Neurooncol
; 133(1): 77-85, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28421460
13.
Large-Scale, Ion-Current-Based Proteomic Investigation of the Rat Striatal Proteome in a Model of Short- and Long-Term Cocaine Withdrawal.
J Proteome Res
; 15(5): 1702-16, 2016 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27018876
14.
Cationizable lipid micelles as vehicles for intraarterial glioma treatment.
J Neurooncol
; 128(1): 21-28, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903015
15.
Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells.
J Pharmacokinet Pharmacodyn
; 42(5): 477-96, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26252969
16.
Transient cerebral hypoperfusion assisted intraarterial cationic liposome delivery to brain tissue.
J Neurooncol
; 118(1): 73-82, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24664370
17.
Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection.
J Neurooncol
; 120(3): 489-97, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25195130
18.
Integrated PK/PD Modeling Relates Smoothened Inhibitor Biomarkers to The Heterogeneous Intratumor Disposition of Cetuximab in Pancreatic Cancer Tumor Models.
J Pharm Sci
; 113(1): 72-84, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37844759
19.
Expression of fibroblast growth factor receptor 1 correlates inversely with the efficacy of single-agent fibroblast growth factor receptor-specific inhibitors in pancreatic cancer.
Br J Pharmacol
; 181(9): 1383-1403, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994108
20.
Systems Pharmacodynamic Model of Combined Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways.
J Pharm Sci
; 113(1): 235-245, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37918792