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1.
Clin Radiol ; 78(1): 55-60, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36307234

RESUMO

PURPOSE: We evaluated the effectiveness of transarterial embolization (TAE) for intractable postpartum hemorrhage in patients with disseminated intravascular coagulation (DIC) despite emergency hysterectomy. MATERIALS AND METHODS: We retrospectively assessed TAE performed after emergency hysterectomy in 15 patients between July 2008 and January 2022. Underlying condition, technical success, clinical success, angiographic findings, laboratory findings, pregnancy-modified DIC score (The International Society on Thrombosis and Haemostasis), blood transfusion, ICU (Intensive care unit) admission day, hospital day, in-hospital mortality, and long-term sequelae were evaluated. RESULTS: All patients were diagnosed with DIC before embolization, with a 43.9 mean DIC score. All patients showed positive angiographic findings for active bleeding. Thirty-eight bleeding arteries were confirmed. The remnant uterine artery (n=25) was the most common focus of persistent bleeding, followed by the cervicovaginal artery (n=6), pudendal artery (n=3), obturator artery (n=2), vesical artery (n=1), and unspecified artery from the internal iliac artery (n=1). Technical and clinical success rates were 100% (15/15) and 93.3% (14/15), respectively. Mean nadir hemoglobin (Hb) level before embolization was 4.9 g/dL. All patients underwent massive transfusion before embolization (mean 33.2 packs of RBC). Postoperatively, a smaller amount of blood was transfused than before the procedure (mean 10.6 packs of RBC). Mean nadir Hb level after embolization was 8.2 g/dL. There was one instance each of in-hospital death, hypoxic brain damage, and ischemic acute kidney injury. CONCLUSION: Despite hysterectomy for postpartum bleeding, there could be multiple residual or uncontrolled bleeding foci, especially in case of DIC, for which TAE could be an effective treatment.


Assuntos
Coagulação Intravascular Disseminada , Embolização Terapêutica , Hemorragia Pós-Parto , Gravidez , Feminino , Humanos , Hemorragia Pós-Parto/diagnóstico por imagem , Hemorragia Pós-Parto/terapia , Estudos Retrospectivos , Coagulação Intravascular Disseminada/complicações , Coagulação Intravascular Disseminada/terapia , Coagulação Intravascular Disseminada/diagnóstico , Mortalidade Hospitalar , Embolização Terapêutica/métodos , Histerectomia , Artéria Uterina , Resultado do Tratamento
2.
Br J Radiol ; 79(942): 529-35, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16714758

RESUMO

We report two cases of deep tracheal laceration in female patients after balloon dilation for benign tracheobronchial stenosis. Immediate post-procedure bronchoscopy and CT including 3D reconstructions showed deep lacerations in the posterior tracheal wall. Clinically, the patients' dyspnoea subsided and there has been no recurrence during follow-up after balloon dilation. On the follow-up 3D-reconstructed CT scans obtained 2 months and 8 months following balloon dilation, respectively, the lacerations had healed completely and there was considerable improvement in lumen size.


Assuntos
Broncopatias/terapia , Cateterismo/efeitos adversos , Traqueia/lesões , Estenose Traqueal/terapia , Adulto , Broncoscopia , Constrição Patológica/terapia , Feminino , Humanos , Lacerações/diagnóstico , Lacerações/etiologia , Tomografia Computadorizada por Raios X , Traqueia/diagnóstico por imagem
3.
Int J Impot Res ; 13(5): 309-16, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11890520

RESUMO

Despite extensive research into the toxicity of bisphenol A (BPA), no report of its effect on erectile function exists. We performed this study to investigate the effect of BPA on erectile function. New Zealand white rabbits were treated intraperitoneally with 150 mg/kg of BPA every other day for 12 days (cumulative dose of 900 mg/kg). Four and 8 weeks after administration of BPA, the contractions and relaxation of cavernosal tissue strips were significantly suppressed in the BPA-treated animals compared to the control animals. Histologically, thickening of tunica albuginea, subtunical deposition of fat and decreased sinusoidal space with consequent increase of trabecular smooth muscle content were observed in the BPA-treated animals. These results suggest that xenoestrogen BPA may affect the erectile function through evident histological changes of the penis.


Assuntos
Estrogênios não Esteroides/farmacologia , Ereção Peniana/efeitos dos fármacos , Pênis/efeitos dos fármacos , Pênis/patologia , Fenóis/farmacologia , Animais , Compostos Benzidrílicos , Estrogênios não Esteroides/administração & dosagem , Técnicas In Vitro , Injeções Intraperitoneais , Contração Isométrica/efeitos dos fármacos , Masculino , Fenóis/administração & dosagem , Coelhos , Valores de Referência
4.
Br J Radiol ; 86(1023): 20120387, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23418206

RESUMO

OBJECTIVE: The purpose of our study was to assess the extrarenal length of renal arterial branches and tumour-feeding arteries on multidetector CT (MDCT) angiography, in addition to the perihilar branching patterns, with relevance to segmental artery clamping. METHODS: MDCT angiograms of 64 patients with renal masses <4 cm were retrospectively reviewed by 2 radiologists. The perihilar branching patterns of the single main renal artery were assessed according to the number of pre-segmental and segmental arteries. The extrarenal lengths of segmental plus pre-segmental arteries and the tumour-feeding arteries, measured on volume-rendered images, were compared according to the vascular segmentation and the tumour location, respectively. RESULTS: In the 116 kidneys, 1 pre-segmental plus 5 segmental arteries (n=48) was the most common branching pattern. The mean extrarenal length of the inferior segmental plus pre-segmental arteries (33.05 mm) and the posterior segmental plus pre-segmental arteries (32.30 mm) was longer than any of the other segmental plus pre-segmental arteries (apical, 23.87 mm; superior, 26.80 mm; middle, 29.23 mm) (p<0.05). The mean extrarenal length of the lower pole tumour-feeding arteries (35.94 mm) was longer than those of the upper and mid-pole tumour-feeding arteries (24.95 mm, 29.62 mm), with significant difference between the lower and the upper pole tumour-feeding arteries (p<0.05). CONCLUSION: Tumours in the lower pole, supplied by the inferior or posterior segmental artery, may be more amenable to segmental artery clamping. ADVANCES IN KNOWLEDGE: MDCT angiography with volume rendering can demonstrate the extrarenal length of tumour-feeding arteries and may help in determining the accessibility for segmental artery clamping.


Assuntos
Neoplasias Renais/irrigação sanguínea , Neoplasias Renais/diagnóstico por imagem , Artéria Renal/anatomia & histologia , Feminino , Humanos , Imageamento Tridimensional , Neoplasias Renais/patologia , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada Multidetectores , Tratamentos com Preservação do Órgão , Artéria Renal/diagnóstico por imagem , Estudos Retrospectivos
5.
Br J Radiol ; 79(943): e8-11, 2006 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16823055

RESUMO

Complete eversion and prolapse of the urinary bladder is extremely rare. To the best of our knowledge, the imaging findings of complete bladder eversion have not been documented in the literature. Here, we report a case of complete eversion and prolapse of the urinary bladder demonstrated on MRI. Concurrent primary adenocarcinoma was found in the thickened wall of the everted urinary bladder.


Assuntos
Adenocarcinoma/diagnóstico , Neoplasias da Bexiga Urinária/diagnóstico , Adenocarcinoma/cirurgia , Idoso , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Prolapso , Neoplasias da Bexiga Urinária/cirurgia
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