Detalhe da pesquisa
1.
Clustered Mutation Signatures Reveal that Error-Prone DNA Repair Targets Mutations to Active Genes.
Cell
; 170(3): 534-547.e23, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753428
2.
Synonymous mutations frequently act as driver mutations in human cancers.
Cell
; 156(6): 1324-1335, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630730
3.
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation.
Nucleic Acids Res
; 52(8): 4393-4408, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587182
4.
Genomics reveal unknown mutation-promoting agents at global sites.
Nature
; 629(8013): 767-768, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38773293
5.
To NMD or Not To NMD: Nonsense-Mediated mRNA Decay in Cancer and Other Genetic Diseases.
Trends Genet
; 37(7): 657-668, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277042
6.
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells.
PLoS Biol
; 19(3): e3001176, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33788831
7.
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors.
BMC Biol
; 21(1): 92, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095494
8.
Spectrum of DNA mismatch repair failures viewed through the lens of cancer genomics and implications for therapy.
Clin Sci (Lond)
; 136(5): 383-404, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35274136
9.
Differential DNA mismatch repair underlies mutation rate variation across the human genome.
Nature
; 521(7550): 81-4, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707793
10.
Passenger mutations accurately classify human tumors.
PLoS Comput Biol
; 15(4): e1006953, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30986244
11.
The landscape of microbial phenotypic traits and associated genes.
Nucleic Acids Res
; 44(21): 10074-10090, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27915291
12.
Extensive complementarity between gene function prediction methods.
Bioinformatics
; 32(23): 3645-3653, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27522084
13.
Hydroxymethylated cytosines are associated with elevated C to G transversion rates.
PLoS Genet
; 10(9): e1004585, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211471
14.
The Code of Silence: Widespread Associations Between Synonymous Codon Biases and Gene Function.
J Mol Evol
; 82(1): 65-73, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538122
15.
Phyletic profiling with cliques of orthologs is enhanced by signatures of paralogy relationships.
PLoS Comput Biol
; 9(1): e1002852, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23308060
16.
Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers.
Nat Cancer
; 5(2): 330-346, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200245
17.
Nucleoid-associated proteins affect mutation dynamics in E. coli in a growth phase-specific manner.
PLoS Comput Biol
; 8(12): e1002846, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23284284
18.
Translational selection is ubiquitous in prokaryotes.
PLoS Genet
; 6(6): e1001004, 2010 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20585573
19.
Proton and alpha radiation-induced mutational profiles in human cells.
Sci Rep
; 13(1): 9791, 2023 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328655
20.
NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects.
Clin Cancer Res
; 29(2): 422-431, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346689