Detalhe da pesquisa
1.
Human parainfluenza virus 3 vaccine candidates attenuated by codon-pair deoptimization are immunogenic and protective in hamsters.
Proc Natl Acad Sci U S A
; 121(25): e2316376121, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38861603
2.
The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells.
PLoS Pathog
; 15(8): e1007963, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381610
3.
Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV G Protein.
J Virol
; 93(7)2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30651356
4.
Attenuated Human Parainfluenza Virus Type 1 Expressing the Respiratory Syncytial Virus (RSV) Fusion (F) Glycoprotein from an Added Gene: Effects of Prefusion Stabilization and Packaging of RSV F.
J Virol
; 91(22)2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835504
5.
Attenuated Human Parainfluenza Virus Type 1 Expressing Ebola Virus Glycoprotein GP Administered Intranasally Is Immunogenic in African Green Monkeys.
J Virol
; 91(10)2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250127
6.
Improved Prefusion Stability, Optimized Codon Usage, and Augmented Virion Packaging Enhance the Immunogenicity of Respiratory Syncytial Virus Fusion Protein in a Vectored-Vaccine Candidate.
J Virol
; 91(15)2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539444
7.
Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector.
J Virol
; 90(21): 10022-10038, 2016 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27581977
8.
Attenuated Human Parainfluenza Virus Type 1 (HPIV1) Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus (RSV) as a Bivalent HPIV1/RSV Vaccine.
J Virol
; 89(20): 10319-32, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26223633
9.
The aberrant gene-end transcription signal of the matrix M gene of human parainfluenza virus type 3 downregulates fusion F protein expression and the F-specific antibody response in vivo.
J Virol
; 89(6): 3318-31, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25589643
10.
Enhanced Neutralizing Antibody Response Induced by Respiratory Syncytial Virus Prefusion F Protein Expressed by a Vaccine Candidate.
J Virol
; 89(18): 9499-510, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26157122
11.
Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection.
J Virol
; 88(8): 4237-50, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24478424
12.
The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R.
J Virol
; 85(4): 1495-506, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21123378
13.
Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates.
PLoS One
; 15(2): e0228572, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32045432
14.
Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates.
J Virol
; 82(18): 8965-77, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18614629
15.
Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes.
Virol J
; 4: 67, 2007 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17605811
16.
An improved method for the recovery of recombinant paramyxovirus vaccine candidates suitable for use in human clinical trials.
J Virol Methods
; 141(1): 30-3, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17210187
17.
The C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining Stat1 in perinuclear aggregates at the late endosome.
PLoS One
; 7(2): e28382, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22355301
18.
Evaluation of two chimeric bovine-human parainfluenza virus type 3 vaccines in infants and young children.
Vaccine
; 30(26): 3975-81, 2012 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22178099
19.
The cDNA-derived investigational human parainfluenza virus type 3 vaccine rcp45 is well tolerated, infectious, and immunogenic in infants and young children.
Pediatr Infect Dis J
; 30(10): e186-91, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21829138
20.
Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3' genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates.
Vaccine
; 25(34): 6409-22, 2007 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17658669