Detalhe da pesquisa
1.
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction.
J Am Chem Soc
; 140(6): 2151-2164, 2018 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381352
2.
Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain.
Bioorg Med Chem
; 25(7): 2177-2190, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28284871
3.
Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease.
Bioorg Med Chem Lett
; 26(19): 4739-4742, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27568084
4.
Discovery of novel 2',4'-dimethyl-[4,5'-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2.
Bioorg Med Chem Lett
; 26(20): 4936-4941, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27634196
5.
Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease.
J Med Chem
; 62(17): 8101-8114, 2019 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31386363
6.
Identification and expression-profiling of Xenopus tropicalis miRNAs including plant miRNA-like RNAs at metamorphosis.
FEBS Lett
; 581(16): 3013-8, 2007 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17544400
7.
Rational design, synthesis, and characterization of novel inhibitors for human beta1,4-galactosyltransferase.
J Med Chem
; 48(19): 6054-65, 2005 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16162007
8.
Direct observation of sugar-protein, sugar-sugar, and sugar-water complexes by cold-spray ionization time-of-flight mass spectrometry.
Angew Chem Int Ed Engl
; 44(4): 571-5, 2005 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15597388
9.
The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif.
J Pept Sci
; 13(4): 269-79, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17394123