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1.
Vet Surg ; 47(4): 572-577, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29655175

RESUMO

OBJECTIVE: To determine the efficacy and dermal tolerance of a novel alcohol-based skin antiseptic (ABSA) in horses. STUDY DESIGN: Experimental study. ANIMAL POPULATION: Systemically healthy horses (n = 25) with no history or clinical signs of skin disease. METHODS: Four clipped sites on the abdomen were randomly assigned to a skin preparation protocol: saline (negative control; NC), chlorhexidine gluconate followed by isopropyl alcohol (positive control; PC), saline followed by the ABSA (ABSA A), or a commercially available horse shampoo followed by the ABSA (ABSA B). Microbiological swabs were obtained from each site and cultured on MacConkey and mannitol salt agar plates. Colony-forming units were counted 18-24 hours later. All sites were scored for signs of skin reaction before, immediately after, 1 hour after, and 24 hours after skin preparation. RESULTS: The PC, ABSA A, and ABSA B methods reduced skin microbial burden compared with the NC method (P < .001), but no difference was detected between antiseptic products. Preparation time did not differ between ABSA A and ABSA B methods (P = 0.108); both were faster than the PC method (P < 0.001 for both). Skin reactions were most abundant 24 hours after skin preparation (30.5%), but there was no significant association with antiseptic used, and no horses required veterinary treatment. CONCLUSION: The ABSA preparations tested in this study were as effective and well tolerated as a chlorhexidine gluconate-based method, but required less time in healthy horses. CLINICAL SIGNIFICANCE: The ABSA tested here provides an efficacious, fast-acting, and well-tolerated alternative to achieve skin antisepsis in healthy horses. These results justify further investigation in clinical cases.


Assuntos
2-Propanol/farmacologia , Anti-Infecciosos Locais/farmacologia , Clorexidina/análogos & derivados , Contagem de Colônia Microbiana , Pele/microbiologia , Administração Cutânea , Animais , Anti-Infecciosos Locais/administração & dosagem , Anti-Infecciosos Locais/efeitos adversos , Clorexidina/administração & dosagem , Clorexidina/efeitos adversos , Clorexidina/farmacologia , Fármacos Dermatológicos/administração & dosagem , Fármacos Dermatológicos/efeitos adversos , Fármacos Dermatológicos/farmacologia , Desinfecção/métodos , Cavalos
2.
Vet Rec ; 184(1): 24, 2019 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-30455192

RESUMO

Colic is a common and potentially life-threatening condition of horses. Multiple risk factors have been previously identified and it is known that a careful management routine can help reduce colic rates. The British military working horse population represents a unique cohort of horses that are intensively managed with a strict regimen. This retrospective study examined the incidence and mortality rate of colic within this population, as well as the signalment of affected horses, and compared these with the general population. Data for 717 horses over a five-year period (2008-2012) were analysed. Of these, 163 horses (22.7 per cent) experienced 267 colic episodes and 13 horses (1.8 per cent) died because of colic. Recurrent colic was experienced by 35 per cent (57/163) of horses. The incidence of colic was 11.1 episodes per 100 horse-years and of colic-related death was 0.5 deaths per 100 horse-years. Horses purchased from mainland Europe were more likely to suffer from colic (OR 4.6; P<0.001) and from recurrent colic (OR 6.0; P=0.005) than horses purchased from Ireland. Only 3 per cent (8/267) of colic episodes were treated surgically. It was concluded that the incidences of colic and colic-related deaths within the British military working horse population are similar to those of the general horse population.


Assuntos
Cólica/epidemiologia , Cólica/veterinária , Doenças dos Cavalos/epidemiologia , Serviço Veterinário Militar , Animais , Cólica/mortalidade , Feminino , Doenças dos Cavalos/mortalidade , Cavalos , Incidência , Masculino , Estudos Retrospectivos , Reino Unido/epidemiologia
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