Detalhe da pesquisa
1.
Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer.
Mol Cancer Ther
; 20(2): 263-273, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268569
2.
Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells.
Mol Cancer Ther
; 8(1): 45-54, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19139112
3.
The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors.
Cell Cycle
; 17(9): 1076-1086, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29895190
4.
Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry.
Cell Cycle
; 15(5): 730-9, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26890478
5.
Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776.
Clin Cancer Res
; 19(16): 4412-21, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804422
6.
Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition.
Clin Cancer Res
; 17(11): 3706-15, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21482692