Detalhe da pesquisa
1.
Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb randomized double-blind vehicle-controlled parallel-group study.
Br J Dermatol
; 189(1): 33-41, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972293
2.
Efficacy and safety of topical brepocitinib for the treatment of mild-to-moderate atopic dermatitis: a phase IIb, randomized, double-blind, vehicle-controlled, dose-ranging and parallel-group study.
Br J Dermatol
; 187(6): 878-887, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35986699
3.
Oral tyrosine kinase 2 inhibitor PF-06826647 demonstrates efficacy and an acceptable safety profile in participants with moderate-to-severe plaque psoriasis in a phase 2b, randomized, double-blind, placebo-controlled study.
J Am Acad Dermatol
; 87(2): 333-342, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35398218
4.
Evaluation of a Janus kinase 1 inhibitor, PF-04965842, in healthy subjects: A phase 1, randomized, placebo-controlled, dose-escalation study.
Br J Clin Pharmacol
; 84(8): 1776-1788, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29672897
5.
Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile.
Brain
; 139(Pt 4): 1052-65, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26920677
6.
Efficacy and Safety of PF-07038124 in Patients With Atopic Dermatitis and Plaque Psoriasis: A Randomized Clinical Trial.
JAMA Dermatol
; 160(2): 156-163, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117526
7.
Safety, Tolerability, and Pharmacokinetics of PF-06823859, an Anti-Interferon ß Monoclonal Antibody: A Randomized, Phase I, Single- and Multiple-Ascending-Dose Study.
Clin Pharmacol Drug Dev
; 10(3): 307-316, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33352008
8.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Liver-Targeting Acetyl-CoA Carboxylase Inhibitor (PF-05221304): A Three-Part Randomized Phase 1 Study.
Clin Pharmacol Drug Dev
; 9(4): 514-526, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065514
9.
Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations.
Drugs R D
; 20(1): 23-37, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32130679
10.
Phase 1 trial of a 20-valent pneumococcal conjugate vaccine in healthy adults.
Vaccine
; 37(42): 6201-6207, 2019 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495592
11.
Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects.
Clin Ther
; 38(6): 1401-1416, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27085586
12.
First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430.
J Nucl Med
; 57(9): 1388-95, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27103022
13.
Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.
Sci Transl Med
; 8(335): 335ra56, 2016 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099175
14.
Hearing loss in migrant agricultural workers.
J Agromedicine
; 10(4): 9-17, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16702119