Detalhe da pesquisa
1.
Preclinical Serological Signatures are Associated With Complicated Crohn's Disease Phenotype at Diagnosis.
Clin Gastroenterol Hepatol
; 21(11): 2928-2937.e12, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787834
2.
Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis.
Gastroenterology
; 159(1): 96-104, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32165208
3.
High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.
PLoS Genet
; 13(1): e1006565, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129359
4.
Gene Expression Signature for Prediction of Golimumab Response in a Phase 2a Open-Label Trial of Patients With Ulcerative Colitis.
Gastroenterology
; 155(4): 1008-1011.e8, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29981298
5.
Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease Tissue.
J Pediatr Gastroenterol Nutr
; 67(1): 45-52, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401083
6.
Inflammatory Bowel Disease Clusters Within Affected Sibships in Ashkenazi Jewish Multiplex Families.
Gastroenterology
; 159(1): 381-382, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32199878
7.
ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation.
Proc Natl Acad Sci U S A
; 107(17): 7692-7, 2010 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351256
8.
Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases.
Biochem J
; 436(2): 241-51, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21426301
9.
Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study.
Biophys J
; 96(6): 2321-34, 2009 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19289058
10.
High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease.
J Crohns Colitis
; 13(4): 462-471, 2019 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445421
11.
Cohort profile of the PRoteomic Evaluation and Discovery in an IBD Cohort of Tri-service Subjects (PREDICTS) study: Rationale, organization, design, and baseline characteristics.
Contemp Clin Trials Commun
; 14: 100345, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30989149
12.
Fecal Microbiota Signatures Are Associated with Response to Ustekinumab Therapy among Crohn's Disease Patients.
mBio
; 9(2)2018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29535202
13.
A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Nat Genet
; 49(10): 1437-1449, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28892060
14.
Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci.
Clin Transl Gastroenterol
; 7(6): e177, 2016 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27336838
15.
Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype.
Biotechnol J
; 8(12): 1452-64, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24318637
16.
Structural systems biology and multiscale signaling models.
Ann Biomed Eng
; 40(11): 2295-306, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539148
17.
Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.
Cancers (Basel)
; 3(1): 1195-231, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21701703
18.
Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation.
Cancer Res J
; 4(4): 1-35, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-25346782
19.
A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network.
Mol Biosyst
; 7(6): 2066-80, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21509365