Investigation ways of causes needle sticks injuries, risk factors affecting on health and ways to preventive.

Needle sticks injuries (NSIs) has caused many health concerns, including the widespread infection disease. Needle sticks injuries can have high threaten health human especially, all those who are in contact with health and medical centers. The purpose of this review study was the determination the effects of needle sticks injuries (NSIs) on health care worker and patents. In this a review study of literature studied conducted on international databases included Google Scholar, ISI/WOS (Web of Science), Springer, Scopus, Medline/PubMed. The literature signs a notable undesirable affect from potential needle sticks injuries related to ways to preventive and risks factors among patents and health care worker. The literature was shown needle stick injuries can cause with a variety of ways including needle recapping, non-standard safety boxes, thin gloves, and inadequate personal protective equipment. According to the result this study, needle stick injuries can transfer infectious disease (Human Immunodeficiency viruses [HIV], Hepatitis C virus [HCV]) and increase risk health on health care worker and patients. According to research related to the subject, the ways to prevent reduce needle sticks include personal protective equipment, holding retraining courses for medical staff in the direction to raise awareness can significantly reduce cases of needle sticks injuries. Further research using more sophisticated methodology is warranted.

Optimization of doubly-fed induction generator (DFIG)based wind turbine to achieve maximum power generation with imperialist competitive algorithm (ICA).

Today, due to the end of fossil fuels and efforts to reduce the use of renewable resources, wind energy is a suitable option for the production of electrical energy due to its high-power generation. To increase the output efficiency of wind turbines, maximum power point tracking techniques are required for wind turbine energy conversion systems. In this research, the maximum power point (MPPT) method for two-way fed wind turbine systems (DFIG) is presented. The performance of the induction generator is presented on both sides of the power and the values of this generator such as speed, torque, voltage, current and maximum power at the time of wind speed changes. The presented work is presented in two scenarios and the model is performed without the algorithm then, a maximum power point tracking method based on the Colonial Competition Algorithm (ICA) has been applied to estimate the power of the two power induction generators. According to the results, it can be said that in the scenario with the algorithm of generating electric power by the turbine, several times in the production state is 9 MW, which is the rate of the turbine's nominal power, while in another scenario, the power generated by the turbine is 85% of the power in the state with the algorithm.

Utilization of additive from waste products with gasoline fuel to operate spark ignition engine.

Impacts of blending fusel oil with gasoline on fuel combustion have been investigated experimentally in the current research to evaluate engine performance improvement and exhaust emission. Tested fuel include F10, F20 (10% and 20% of fusel oil by volume) and pure gasoline as baseline fuel have been used to operate 4-cylinder SI engine at increasing engine speed and constant throttle valve of 45%. The present results reveal a shorter combustion duration and better engine performance with F10 over engine speeds with maximum value of 33.9% for the engine brake thermal efficiency. The lowest BSFC of 251 g/kW h was recorded at 3500 rpm engine speed also with F10. All blended fuel have almost similar COVIMEP. Less NOx emission was measured with F10 at 4500 engine speed compared to gasoline. However, CO emissions reduced while higher CO2 was observed with introducing fusel oil in the blend. Moreover, HC emission increased an average by 11% over speed range and the highest value was achieved with 10% fusel oil addition compared to 20% and pure gasoline. Accordingly, higher oxygen content of fusel oil and octane number contribute to improve combustion of fuel mixture.

Conductive Gels: Properties and Applications of Nanoelectronics.

Conductive gels are a special class of soft materials. They harness the 3D micro/nanostructures of gels with the electrical and optical properties of semiconductors, producing excellent novel attributes, like the formation of an intricate network of conducting micro/nanostructures that facilitates the easy movement of charge carriers. Conductive gels encompass interesting properties, like adhesion, porosity, swelling, and good mechanical properties compared to those of bulk conducting polymers. The porous structure of the gels allows the easy diffusion of ions and molecules and the swelling nature provides an effective interface between molecular chains and solution phases, whereas good mechanical properties enable their practical applications. Due to these excellent assets, conductive gels are promising candidates for applications like energy conversion and storage, sensors, medical and biodevices, actuators, superhydrophobic coatings, etc. Conductive gels offer promising applications, e.g., as soft sensors, energy storage, and wearable electronics. Hydrogels with ionic species have some potential in this area. However, they suffer from dehydration due to evaporation when exposed to the air which limits their applications and lifespan. In addition to conductive polymers and organic charge transfer complexes, there is another class of organic matter called "conductive gels" that are used in the organic nanoelectronics industry. The main features of this family of organic materials include controllable photoluminescence, use in photon upconversion technology, and storage of optical energy and its conversion into electricity. Various parameters change the electronic and optical behaviors of these materials, which can be changed by controlling some of the structural and chemical parameters of conductive gels, their electronic and optical behaviors depending on the applications. If the conjugated molecules with π bonds come together spontaneously, in a relative order, to form non-covalent bonds, they form a gel-like structure that has photoluminescence properties. The reason for this is the possibility of excitation of highest occupied molecular orbital level electrons of these molecules due to the collision of landing photons and their transfer to the lowest unoccupied molecular orbital level. This property can be used in various nanoelectronic applications such as field-effect organic transistors, organic solar cells, and sensors to detect explosives. In this paper, the general introduction of conductive or conjugated gels with π bonds is discussed and some of the physical issues surrounding electron excitation due to incident radiation and the mobility of charge carriers, the position, and role of conductive gels in each of these applications are discussed.

The emerging role of 27-hydroxycholesterol in cancer development and progression: An update.

Oxysterols are cholesterol metabolites generated in the liver and other peripheral tissues as a mechanism of removing excess cholesterol. Oxysterols have a wide range of biological functions, including the regulation of sphingolipid metabolism, platelet aggregation, and apoptosis. However, it has been found that metabolites derived from cholesterol play essential functions in cancer development and immunological suppression. In this regard, research indicates that 27-hydroxycholesterol (27-HC) might act as an estrogen, promoting the growth of estrogen receptor (ER) positive breast cancer cells. The capacity of cholesterol to dynamically modulate signaling molecules inside the membrane and particular metabolites serving as signaling molecules are two possible contributory processes. 27-HC is a significant metabolite produced mainly through the CYP27A1 (Cytochrome P450 27A1) enzyme. 27-HC maintains cholesterol balance biologically by promoting cholesterol efflux via the liver X receptor (LXR) and suppressing de novo cholesterol production through the Insulin-induced Genes (INSIGs). It has been demonstrated that 27-HC is able to function as a selective ER regulator. Moreover, enhanced 27-HC production is in favor of the growth of end-stage malignancies in the brain, thyroid organs, and colon, as shown in breast cancer, probably due to pro-survival and pro-inflammatory signaling induced by unbalanced levels of oxysterols. However, the actual role of 27-HC in cancer promotion and progression remains debatable, and many studies are warranted to be performed to unravel the precise function of these molecules. This review article will summarize the latest evidence on the deleterious or beneficial functions of 27-HC in various types of cancer, such as breast cancer, prostate cancer, colon cancer, gastric cancer, ovarian cancer, endometrial cancer, lung cancer, melanoma, glioblastoma, thyroid cancer, adrenocortical cancer, and hepatocellular carcinoma.

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism.

The accumulating evidence revealed that microbiota plays a significant function in training, function, and the induction of host immunity. Once this interaction (immune system-microbiota) works correctly, it enables the production of protective responses against pathogens and keeps the regulatory pathways essential for maintaining tolerance to innocent antigens. This concept of immunity and metabolic activity redefines the realm of immunometabolism, paving the way for innovative therapeutic interventions to modulate immune cells through immune metabolic alterations. A body of evidence suggests that microbiota-derived metabolites, including short-chain fatty acids (SCFAs) such as butyrate, acetate, and propionate, play a key role in immune balance. SCFAs act on many cell types to regulate various vital biological processes, including host metabolism, intestinal function, and the immune system. Such SCFAs generated by gut bacteria also impact immunity, cellular function, and immune cell fate. This is a new concept of immune metabolism, and better knowledge about how lifestyle affects intestinal immunometabolism is crucial for preventing and treating disease. In this review article, we explicitly focus on the function of SCFAs in the metabolism of immune cells, especially macrophages, neutrophils, dendritic cells (DCs), B cells, T (Th) helper cells, and cytotoxic T cells (CTLs).