Detalhe da pesquisa
1.
Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection.
N Engl J Med
; 387(21): 1957-1968, 2022 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346079
2.
Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B Infection across the Asia-Pacific Region.
Antimicrob Agents Chemother
; 67(1): e0090022, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507675
3.
Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy.
J Hepatol
; 77(4): 967-977, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714812
4.
Efficacy and Safety of Bepirovirsen in Hepatitis B. Reply.
N Engl J Med
; 388(12): 1147-1148, 2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947478
5.
Randomized clinical trials towards a single-visit cure for chronic hepatitis C: Oral GSK2878175 and injectable RG-101 in chronic hepatitis C patients and long-acting injectable GSK2878175 in healthy participants.
J Viral Hepat
; 27(7): 699-708, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096313
6.
A 2-Year, Longitudinal, Prospective Study of the Effects of Eltrombopag on Bone Marrow in Patients with Chronic Immune Thrombocytopenia.
Acta Haematol
; 137(2): 66-72, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28006767
7.
Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): a randomised, multicentre, placebo-controlled trial.
Lancet
; 386(10004): 1649-58, 2015 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231455
8.
Health-related quality of life in thrombocytopenic patients with chronic hepatitis C with or without cirrhosis in the ENABLE-1 and ENABLE-2 studies.
Health Qual Life Outcomes
; 14: 49, 2016 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27004952
9.
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
N Engl J Med
; 367(8): 716-24, 2012 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22913681
10.
Eltrombopag increases platelet numbers in thrombocytopenic patients with HCV infection and cirrhosis, allowing for effective antiviral therapy.
Gastroenterology
; 146(2): 442-52.e1, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24126097
11.
Evaluation of bone marrow reticulin in patients with chronic immune thrombocytopenia treated with eltrombopag: Data from the EXTEND study.
Am J Hematol
; 90(7): 598-601, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801698
12.
Severity of liver disease among chronic hepatitis C patients: an observational study of 4594 patients in five European countries.
J Gastroenterol Hepatol
; 30(2): 364-71, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25088088
13.
Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
J Gastroenterol Hepatol
; 30(8): 1301-8, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25777337
14.
Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir.
Antimicrob Agents Chemother
; 58(11): 6704-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25155600
15.
B-Clear Phase 2b Study Design: Establishing the Efficacy and Safety of Bepirovirsen in Patients with Chronic Hepatitis B Virus Infection.
Adv Ther
; 40(9): 4101-4110, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37393402
16.
Characteristics, Treatment Patterns, and Clinical Outcomes of Chronic Hepatitis B Across 3 Continents: Retrospective Database Study.
Adv Ther
; 40(2): 425-444, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350533
17.
Patient Biochemistry and Treatment Need in Chronic Hepatitis B Virus Infection Across Three Continents: Retrospective Cross-Sectional Cohort Studies.
Infect Dis Ther
; 12(11): 2513-2532, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37432642
18.
Assessment of the pharmacokinetic interaction between eltrombopag and lopinavir-ritonavir in healthy adult subjects.
Antimicrob Agents Chemother
; 56(6): 2846-51, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22391553
19.
Preclinical and Phase 1 Assessment of Antisense Oligonucleotide Bepirovirsen in Hepatitis B Virus-Transgenic Mice and Healthy Human Volunteers: Support for Clinical Dose Selection and Evaluation of Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses.
Clin Pharmacol Drug Dev
; 11(10): 1191-1202, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971951
20.
Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection.
Gastroenterology
; 138(4): 1365-73, 1373.e1-2, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20004661