Detalhe da pesquisa
1.
Heterocyclic ring expansion yields anthraquinone derivatives potent against multidrug resistant tumor cells.
Bioorg Chem
; 127: 105925, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728293
2.
Water-Soluble Heliomycin Derivatives to Target i-Motif DNA.
J Nat Prod
; 84(5): 1617-1625, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33974416
3.
Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers.
Biochemistry
; 57(5): 742-752, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29286643
4.
Synthesis and antitumor activity of cyclopentane-fused anthraquinone derivatives.
Eur J Med Chem
; 265: 116103, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38176358
5.
Thiadiazole-, selenadiazole- and triazole-fused anthraquinones as G-quadruplex targeting anticancer compounds.
Eur J Med Chem
; 268: 116222, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38387333
6.
Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells.
Elife
; 122024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38567911
7.
Hybrid Molecules of Azithromycin with Chloramphenicol and Metronidazole: Synthesis and Study of Antibacterial Properties.
Pharmaceuticals (Basel)
; 17(2)2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399402
8.
Computational and Biophysical Characterization of Heterocyclic Derivatives of Anthraquinone against Human Aurora Kinase A.
ACS Omega
; 7(44): 39603-39618, 2022 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385832
9.
Antibiotic heliomycin and its water-soluble 4-aminomethylated derivative provoke cell death in T24 bladder cancer cells by targeting sirtuin 1 (SIRT1).
Am J Cancer Res
; 12(3): 1042-1055, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411221
10.
Bis(chloroacetamidino)-Derived Heteroarene-Fused Anthraquinones Bind to and Cause Proteasomal Degradation of tNOX, Leading to c-Flip Downregulation and Apoptosis in Oral Cancer Cells.
Cancers (Basel)
; 14(19)2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230644
11.
Design, Synthesis and In Vitro Investigation of Cabozantinib-Based PROTACs to Target c-Met Kinase.
Pharmaceutics
; 14(12)2022 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36559322
12.
Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype.
Eur J Med Chem
; 221: 113521, 2021 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34082225
13.
Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration.
Pharmaceuticals (Basel)
; 13(5)2020 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32353946
14.
Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties.
Eur J Med Chem
; 199: 112294, 2020 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32428792
15.
Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular Carcinoma Cells.
Cancers (Basel)
; 11(3)2019 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30909652
16.
New anthra[2,3-b]furancarboxamides: A role of positioning of the carboxamide moiety in antitumor properties.
Eur J Med Chem
; 165: 31-45, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30659997
17.
Advances in the Discovery of Anthraquinone-Based Anticancer Agents.
Recent Pat Anticancer Drug Discov
; 13(2): 159-183, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29210664
18.
Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency.
Recent Pat Anticancer Drug Discov
; 13(4): 469-472, 2018 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30039764
19.
Tri-armed ligands of G-quadruplex on heteroarene-fused anthraquinone scaffolds: Design, synthesis and pre-screening of biological properties.
Eur J Med Chem
; 159: 59-73, 2018 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30268824
20.
New antitumor anthra[2,3-b]furan-3-carboxamides: Synthesis and structure-activity relationship.
Eur J Med Chem
; 148: 128-139, 2018 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29459273