Detalhe da pesquisa
1.
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.
Lancet Oncol
; 25(3): 317-325, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342115
2.
miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.
EMBO J
; 37(13)2018 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871889
3.
Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.
Br J Cancer
; 125(12): 1599-1601, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294894
4.
Progesterone receptor modulates ERα action in breast cancer.
Nature
; 523(7560): 313-7, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26153859
5.
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer.
Breast Cancer Res
; 22(1): 87, 2020 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787886
6.
Elevated levels of tumour apolipoprotein D independently predict poor outcome in breast cancer patients.
Histopathology
; 76(7): 976-987, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31994214
7.
Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells.
J Mammary Gland Biol Neoplasia
; 24(1): 99-108, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30099649
8.
An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy.
Int J Cancer
; 144(5): 1151-1159, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30288742
9.
Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b.
Br J Cancer
; 119(11): 1316-1325, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30410061
10.
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.
Nucleic Acids Res
; 43(12): 5880-97, 2015 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25908785
11.
IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor.
BMC Cancer
; 16: 141, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26907477
12.
Corrigendum: Progesterone receptor modulates ERα action in breast cancer.
Nature
; 526(7571): 144, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245370
13.
Hormone-sensing mammary epithelial progenitors: emerging identity and hormonal regulation.
J Mammary Gland Biol Neoplasia
; 20(1-2): 75-91, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390871
14.
Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.
EMBO J
; 30(15): 3019-27, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21701558
15.
Hsp90: still a viable target in prostate cancer.
Biochim Biophys Acta
; 1835(2): 211-8, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23287571
16.
Selective inhibition of CDK9 in triple negative breast cancer.
Oncogene
; 43(3): 202-215, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001268
17.
The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
Genome Biol
; 25(1): 44, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317241
18.
Library size confounds biology in spatial transcriptomics data.
Genome Biol
; 25(1): 99, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637899
19.
ACSM1 and ACSM3 regulate fatty acid metabolism to support prostate cancer growth and constrain ferroptosis.
Cancer Res
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38657108
20.
Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.
Int J Cancer
; 133(12): 2812-23, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23740762