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1.
Org Biomol Chem ; 18(42): 8746, 2020 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-33084714

RESUMO

Correction for 'A multi-component reaction for the synthesis of pyrido [1,2-b] isoquinoline derivatives via the [3 + 2] cycloaddition reaction between alkynes and in situ generated isoquinolinium ylides' by Sundar S. Shinde et al., Org. Biomol. Chem., 2019, 17, 4121-4128, DOI: 10.1039/C9OB00560A.

2.
Org Biomol Chem ; 17(16): 4121-4128, 2019 04 17.
Artigo em Inglês | MEDLINE | ID: mdl-30968921

RESUMO

An efficient and one-pot tandem procedure for the synthesis of fused ethanopyrido [1,2-b] isoquinoline derivatives from ninhydrin, proline and alkynes has been developed. This strategy exhibits an unprecedented [3 + 2] cycloaddition reaction between alkynes and isoquinolinium ylide (1,3 dipole) generated in situ from proline and ninhydrin. This newly developed methodology features simple operation and is metal free. In this methodology overall three new C-C bonds, two C-N bonds, and three new rings are formed in a single step process.

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