Detalhe da pesquisa
1.
Regulation of integrin and extracellular matrix genes by HNRNPL is necessary for epidermal renewal.
PLoS Biol
; 19(9): e3001378, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543262
2.
CDK12 Is Necessary to Promote Epidermal Differentiation Through Transcription Elongation.
Stem Cells
; 40(4): 435-445, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35325240
3.
RAS-mediated suppression of PAR3 and its effects on SCC initiation and tissue architecture occur independently of hyperplasia.
J Cell Sci
; 133(23)2020 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33172988
4.
Microbial biofilm ecology, in silico study of quorum sensing receptor-ligand interactions and biofilm mediated bioremediation.
Arch Microbiol
; 203(1): 13-30, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32785735
5.
Crizotinib-induced anti-cancer activity in human cervical carcinoma cells via ROS-dependent mitochondrial depolarization and induction of apoptotic pathway.
J Obstet Gynaecol Res
; 47(11): 3923-3930, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482598
6.
Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: Where are we today?
Med Res Rev
; 40(6): 2485-2565, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32691504
7.
Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation.
Bioorg Chem
; 95: 103524, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31918396
8.
Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents.
Bioorg Med Chem
; 27(14): 3156-3166, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176571
9.
Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides.
Mol Divers
; 21(1): 163-174, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039637
10.
Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1.
Mol Cancer
; 15(1): 64, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756327
11.
Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-ß-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease.
Bioorg Med Chem
; 24(16): 3829-41, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27353888
12.
Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
Bioorg Med Chem
; 24(12): 2777-88, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27157006
13.
Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors.
J Enzyme Inhib Med Chem
; 31(sup2): 174-179, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27314170
14.
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Bioorg Med Chem Lett
; 25(5): 1092-9, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25619635
15.
Multifunctional novel Diallyl disulfide (DADS) derivatives with ß-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
Bioorg Med Chem
; 23(19): 6389-403, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26337018
16.
Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.
Bioorg Med Chem
; 23(5): 1135-48, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25624107
17.
Synthesis and characterization of Fe3O4@SiO2@PDA@Ag core-shell nanoparticles and biological application on human lung cancer cell line and antibacterial strains.
Artif Cells Nanomed Biotechnol
; 52(1): 46-58, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38156875
18.
Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.
Biomed Pharmacother
; 174: 116484, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565058
19.
Determination of dissociation constant of the NFκB p50/p65 heterodimer using fluorescence cross-correlation spectroscopy in the living cell.
Biochem Biophys Res Commun
; 436(3): 430-5, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23751347
20.
Structure-based pharmacophore mapping and virtual screening of natural products to identify polypharmacological inhibitor against c-MET/EGFR/VEGFR-2.
J Biomol Struct Dyn
; 41(7): 2956-2970, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35196966